两种方法处理化疗药物渗漏的效果观察

Effect Observation on Treatment of Leakage of Chemotherapeutic Agents with Two Methods

目的:探讨一点注射法局部封闭化疗药物渗漏的效果及其临床实用性。方法:将发生化疗药物渗漏的60例患者随机分成两组,实验组采用一点注射法进行局部封闭;对照组采用传统的多点环行封闭法,观察两组患者皮肤疼痛消失时间,局部肿胀硬结消失时间,静脉弹性恢复时间。结果:两组治疗效果差异无统计学意义(P>0.05),但两组注射后穿刺点感染率、渗血、渗液率差异有显著性(P<0.05、P<0.01)。结论:利用一点注射法疗效好,有减轻患者痛苦,减少穿刺点感染、渗血、渗液,简化操作程序等优点,可在临床上推广应用。

Objective： To investigate the effect and clinical value on the treatment of leakage of chemotherapeutic agents by local blocking with one-point injection. Methods： Sixty patients with leakage of chemotherapeutic agents were divided into two groups randomly. The experimental group were treated by lo- cal blocking with one-point injection. The control group was treated by local blocking with traditional ring-shaped blockade. The disappearing time of local skin ache and edema indurations, and the recovery time of venous elasticity were compared observed. Result： There were no significant differences between two groups in treatment effect （P〉O.05）. The incidence of the infection, errhysis and seepage around the puncture point in experimental group was significantly less than control group （P〈0.05, P〈0.01）. Conclusion： The effect of one-point injection is better. This simple technique procedure can alleviate patients＇ suffering, reduce untoward effect such as the infection, errhysis and seepage around the puncture point, and is worth popularizing in clinical practice.