摘要
血管内皮生长因子-C（VEGF-C）可以与血管及淋巴管内皮上的特异性受体结合，加速肺癌的形成及转移。同时对恶性胸腔积液的生成、免疫调节因子的表达也有着特殊作用。目前国内外研究均显示VEGF-C的抑制有望成为治疗肺癌的新靶点。
Vascular endothelial growth factor - C （ VEGF- C） binds to special receptors on the vessel and lymphatic endothelium to accelerate the formation and metastasis of lung cancer. It shows specific action on malignant pleural effusion formation and immuno-regulation factor expression. It is reported that inhibition of VEGF-C would be a target point in lung cancer therapy.
出处
《国际肿瘤学杂志》
CAS
2009年第6期434-436,共3页
Journal of International Oncology
关键词
血管内皮生长因子C
肺肿瘤
胸腔积液
Vascular endothelial growth factor C
Lung neoplasms
Pleural effusion
