微波消解电感耦合等离子体质谱法测定3种中药材中4种重金属含量

Determination of Four Heavy Metals in Three Traditional Chinese Medicines by ICP-MS

目的建立电感耦合等离子体质谱（ICP-MS）法测定淫羊藿、当归、黄芪3种中药材中铅（Pb）、镉（Cd）、铜（Cu）、砷（As）含量的方法。方法样品经微波消解，用ICP-MS测定淫羊藿、当归、黄芪3种中药材中上述4种元素含量。结果对于所测元素，校准曲线的相关系数r〉0.999 6，回收率为96.3%-112.0%，RSD〈7.26%。测定结果显示，被测的元素含量因不同药材而存在较大差异，各元素的变动范围Pb 0.3062-0.8062μg·g^-1，Cd 0.0409-0.0804μg·g^-1，Cu 14.2600-18.2300μg·g^-1，As 0.2464-1.1523μg·g^-1。结论研究所建立的方法具有简便、快速、准确、灵敏度高的优点，可用于中药材的质量控制。

Objective To establish an ICP - MS method for the determination of heavy metals, including Pb, Cd, Cu, As, in three traditional Chinese medicines, Herba Epimedh, Radix Angelicae Sinensis, Radix Astragali. Methods The samples were digested by closed - versel microwave. The four heavy metals were directly analyzed by ICP - MS. Results For all of the analyzed heavy metals, the correlative coefficients of the calibration curves were over 0. 999 6. The recovery rates of the procedure were 96.3% - 112.0% , and its RSD was lower than 7.26%. Under the given analytical conditions, the results showed that the contents of the four elements varied in these different medicines, for element Pd, ranging between 0. 306 2 - 0.806 2 μg·g^-1 , Cd 0. 040 9 - 0. 080 4 μg·g^-1, Cu14.2600-18.2300 μg·g^-1, As 0. 2464-1.1523 μg·g^-1 , respectively. Conclusion This method is convenient, quick, accurate and highly sensitive. The method can be used for the quality control of trace elements in traditional Chinese medicines.