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苦瓜降糖作用研究 被引量:9

Hypoglycemic effect of Momordica Charantia
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摘要 近年国内外对苦瓜研究发现其含有三萜类、植物甾醇、苷类、甾体类和肽类等多种降血糖活性成分。苦瓜的果汁、水、醇及醚等多种提取物具有降糖作用。多项研究表明苦瓜的上述成分可通过抑制葡萄糖在小肠黏膜的吸收、促进葡萄糖的利用、促进胰岛素的分泌和类胰岛素作用、保护胰岛β细胞并促进β细胞的增殖抑制其凋亡,以及免疫调节作用来降低血糖达到治疗糖尿病的目的。 In recent years,many studies found that Momordica charantia contains many active hypoglycemic ingredients such as:triterpenes.phytosterols.glycosides.steroid.peptide etc.Momordica charantia juice, water, alcohol and ether extracts have various hypoglycemic effect.A number of studies show that the components of Momordica charantia can be attributed to in- hibitted glucose absorption in the intestinal mueosa, increased glucose utilization, promoted insulin secretion,promoted prolifera- tion and inhibitted apoptosis of pancreatic β cell,and has insulin-like role, the protection of β-cells and immune regulation effect.So Momordica charantia can reduce blood sugar to achieve the purpose of treatment of diabetes.
出处 《中医药导报》 2009年第6期109-112,共4页 Guiding Journal of Traditional Chinese Medicine and Pharmacy
关键词 苦瓜 降糖作用 机制 Momordica charantia Hypoglycemic effect
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参考文献22

  • 1Harinantenaina L,Tanaka M,Takaoka S,et al.Momordica charantia constituents and antidinhetic screening of the isolated major compounds[J].Chem Pharm Bull (Tokyo),2006,54(7):1017-1021
  • 2侣丽红,赵余庆.苦瓜的降血糖作用及活性成分的研究[J].中药材,2002,25(6):449-451. 被引量:37
  • 3Oishi Y,Sakamoto T,Udagawa H,et al.Inhibition of Increases in Blood Glucose and Serum Neutral Fat by Momordica charantia Saponin Fraction[J].Biosci Biotechnol Biochem,2007,71(3):735-740
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  • 8Ahmed I,Adeghate E,Cummings E,et al.Beneficial effects and mechanism of action of Momordica charantia juice in the treatment of streptozotocin-induced diabetes mellitus in rat[J].Mol Cell Biochem,2004,261(1-2):63-70
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