脊髓室管膜下瘤5例并文献复习

Subependymoma of the spinal cord:a report of 5 cases and a review of literatures

目的探讨脊髓室管膜下瘤的临床特点和治疗方法。方法回顾性分析2003-01～2007-06我院收治的5例脊髓室管膜下瘤,并结合文献进行分析。结果5例患者中2例全切除,3例近全切除,术后5例患者均得到随访,其中1例患者于术后6个月复发,1例患者术后8个月在原发病变下段脊髓又出现新病灶,再行手术切除肿瘤,1例病变次全切除患者术后行放疗,未显示有复发;4例患者预后较好,1例患者预后差。结论脊髓室管膜下瘤少见,核磁共振有助于术前诊断,手术为室管膜下瘤的最佳治疗方法,患者术后预后相对较好。

Objective To explore the clinical characteristics and treatment of subependymoma of the spinal cord. Methods A total of 5 cases of subependymoma from January 2003 to June 2007 were enrolled. Also the literatures were reviewed. Results Among 5 cases,total removal was performed in 2 cases and subtotal in 3 cases. All patients were followed up. Of 5 cases, one case recurred after the operation for 6 months;one case was found a new lesion in the inferior segment of primary lesions after total removal for 8 months and further surgery was performed to remove the tumor;one case with subtotal removal undergoing radiotherapy did not recur. Four patients had achieved a good functional outcome, while one patient was poor. Conclusion MRI may contribute to diagnose the subependymoma of spinal cord. The best treatment of subependymoma is surgical resection with relatively good outcome.