期刊文献+

axin、β-catenin在Wnt信号转导途径中的调节机制 被引量:6

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出处 《医学研究杂志》 2009年第7期8-11,共4页 Journal of Medical Research
基金 广东省科技厅产业技术研究与开发资金(2007B031513002)
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参考文献14

  • 1Kikuchi A. Roles of Axin in the Wnt signalling pathway. Cell Signal, 1999,11(11) :777 -788.
  • 2Luo W, Lin SC. Axin:a master scaffold for multiple signaling pathways. Neurosignals,2004,13 (3) :99 - 113.
  • 3Zeng L,Fagotto F,Zhang T,et al. The mouse Fused locus encodes Axin,an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation. Cell,1997,90( 1 ) :181 - 192.
  • 4Kikuchi A. Modulation of Wnt signaling by Axin and AxiL Cytokine Growth Factor Rev, 1999,10 (324) :255 - 265.
  • 5Kishida S, Yamamoto H, Ikeda S, et al. Axin, a negative regulator of the writ signaling pathway,directly interacts with adenomatous polyposis coil and regulates the stabilization of betacatenin. J Biol Chem, 1998,273(18) :10823 - 10826.
  • 6Ikeda S, Kishida S, Yamamoto H, et al. Axin, a negative regulator of the Wnt signaling pathway,forms a complex with GSK3beta and beta- catenin and promotes GSK3beta - dependent phosphorylation of beta- catenin. EMBO J,1998,17(5):1371-1384.
  • 7Kadoya T, Kishida S, Fukui A,et al. Inhibition of Wnt signaling pathway by a novel Axin -binding protein. J B iol Chem,2000,275 (47) : 37030 - 37037.
  • 8Nishida T, Kaneko F, Kitagawa M, et al. Characterization of a novel mammalian SUMO - 1/Smt3 - specific isopeptidase, a homologue of rat axam,which is an axinbinding protein promoting betacatenin degradation. J Biol Chem ,2001,276(42 ) :39060 -39066.
  • 9Kadoya T, Yamamoto H, Suzuki T, et al. Desumoylation activity of Axam, a novel Axin - binding protein, is involved in downregulation of beta - catenin. Mol Cell Biol,2002,22 ( 11 ) :3803 - 3819.
  • 10Kishida S,Yamamoto H,Hino S,et al. DIX domains of Dvl and Axin are necessary for protein interactions and their ability to regulate beta- catenin stability. Mol Cell Biol, 1999,19 ( 6 ) :4414 - 4422.

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