摘要
目的:为探索慢性原发性失眠的人格特征及听觉诱发电位(auditory evoked potential,AEP)的强度依赖性。方法:本研究比较了37名慢性原发性失眠患者(失眠组)与44名健康自愿者(对照组)的AEP对声音刺激的强度依赖性。采用Zuckerman感觉寻求量表(Zuckerman's sensationseeking scales,SSS)、Zuckerman-Kuhlman人格问卷(Zuckerman-Kuhlman's personalityquestionnaire,ZKPQ)测量受试者的人格特征,Plutchik-van Praag's抑郁问卷(Plutchik-vanPraag's depression inventory,PVP)测量受试者的心境状态。结果:与对照组比较,失眠组患者神经质-焦虑、PVP得分偏高(P<0.01),冲动、攻击-敌意也偏高(P<0.05);AEP的N1-P2幅度随着刺激强度的增加而增加,在70、80、90、100 dB之间存在差异(P<0.01);ZKPQ活泼得分与80 dB时的N1潜伏期、100 dB时的P2潜伏期呈低等程度相关(r=0.270和r=0.276,P<0.05);感觉寻求量表总分与70、90 dB时的N1-P2幅度有中等程度相关(r=0.3746和r=0.35329,P<0.01);经历寻求与70、80、90 dB时的N1-P2幅度也呈中等相关(r=0.539、r=0.3439,P<0.01),经历寻求与100dB时的N1-P2幅度呈明显相关(r=0.439、r=0.3278,P<0.05);不甘寂寞与ASF斜率呈低等程度负相关(r=-0.282998,P<0.05),危险和冒险寻求与90 dB时的N1-P2幅度有相关(r=0.2789,P<0.05);PVP与70 dB时的N1-P2幅度、80 dB时的N1潜伏期呈负相关(r=-0.3434、r=-0.3158,P<0.05)。结论:慢性原发性失眠患者具有神经质-焦虑、抑郁、攻击-敌意和冲动等人格特质得分增高,且与AEP强度依赖性有关。
Objective: To investigate the personality traits and intensity dependence of auditory evoked potentials (AEPs) in chronic primary insomnia. Methods: Thirty-seven patients with chronic primary insomnia (insomnia group) and 44 healthy subjects (control group) were enrolled in the study. The AEPs were examined in insomnia and control groups; the personality traits were studied by Zuckerman's Sensation Seeking Scales (SSS) and Zuckerman-Kuhlman's Personality Questionnaire (ZKPQ); and the mood states by Plutchik-van Praag's Depression Inventory (PVP). Results: The scores of neuroticism-anxiety and depression in insomnia group were significantly higher than those in control group (P〈0. 01); and the scores of impulsivity and aggression-hostility were also higher than those in control group (P 〈 0.05); N1-P2 amplitude of AEP increased with stimulus intensity,which were significantly different in 70,80, 90,100 dB (P〈0. 01). There were significant correlations between activity and N1 latency at 80 dB,activity and P2 latency at 100 dB(r=0. 270,r=0. 276,P〈0. 05). and between total scores of sensation seeking scale and N1-P2 amplitude(r=0. 3746,r=0. 35329,P〈0.01) at 70 and 90 dB stimulus intensity in insomnia group. There were significant correlations among experience seeking and N1-P2 amplitude,experience seeking and slope rate(P〈0.01) at 70,80,90,100 dB stimulus intensity in insomnia group (r=0. 539,r=0. 3439,r=0. 439,r= 0. 3278). There were significant correlations between sensation seeking of boredom susceptibility and slope rate (r= -0. 282998,P〈0.05) in insomnia group. There were significant correlations between thrill and adventure seeking and N1-P2 amplitude (r=0. 2789, P〈0.05) at 90 dB stimulus intensity in insomnia group; there were significant correlations between PVP and N1-P2 amplitude (r= -0.3434,r=-0.3158,P%0.05) at 70 dB and N1 latency at 80 dB in insomnia group. Conclusions: Chronic primary insomnia sufferers have higher levels of neuroticism-anxiety, depression,aggression-hostility and impulsivity,and some are correlated with stimulus intensity dependence in AEP.
出处
《浙江大学学报(医学版)》
CAS
CSCD
北大核心
2009年第3期289-296,共8页
Journal of Zhejiang University(Medical Sciences)
关键词
入睡和睡眠障碍/心理学
人格
问卷调查
物理刺激
诱发电位
听觉
抑郁/并发症
Sleep initiation and maintenance disorder/psychol
Personality
Questionnaires
Physical stimulation
Evoked potentials ,auditory
Depression/compl