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乳腺癌分子靶向治疗的进展与展望 被引量:7

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出处 《肿瘤基础与临床》 2009年第3期270-271,共2页 journal of basic and clinical oncology
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参考文献16

  • 1Hegde PS,Rusnak D,Bertiaux M,et al.Delineation of molecular mechanisms of sensitivity to Iapatinib in breast canner cell lines using global gene expression profiles[J].Mol Cancer Ther,2007,6 (5):1629-1640.
  • 2Ito Y,Tokudome N,Sugihara T,et al.Does lapstinib,a small-moleeule tyrosine kinase inhibitor,constitute a breakthrough in the treat ment of breast cancer[J].Breast Cancer,2007,14(2):156-162.
  • 3Medina PJ,C,oadin S.Lapatinib:a dual inhibitor of human epidermal growth factor receptor tyrosine kinases[J].Clin Ther,2008,30(8):1426-1447.
  • 4马传栋,沈坤炜,沈镇宙.拉帕替尼治疗乳腺癌的研究进展[J].中华肿瘤杂志,2008,30(5):321-324. 被引量:9
  • 5Lin NU,Diéras V,Paul D,et al.Muhi-eenter phase Ⅱ study of lapatinib in patients with brain metastuses from HER2-positive breast caneer[J].Clin Cancer Res,2009,15(4):1452 -1459.
  • 6Engnl RH,Kaklamani VG.HER2-positive breast cancer:current and future treatment stmtagies[J].Drugs,2007,67 (9):1329-1341.
  • 7Porters CC,Walshe JM,Rosing DR,et al.Cardiac toxicity and efficacy of trastuzumab combined with pertuzumab in patients with[corrected] human epidermal growth factor receptor 2-positive metastatic breast cancer[J].Clin Cancer Res,2009,14(9):2710 -2716.
  • 8Albanell J,Montagnt C,Jones ET,et al.A phase Ⅰ study of the safety and pharmacokinetics of the combination of pertuzumab (thuMab 2C4) and capeeitsbine in patients with advanced solid tumors[J].Clin Cancer Res,2008,14(9):2726 -2731.
  • 9刘磊,赵羲和,李凯.帕妥珠单抗与厄洛替尼对荷瘤小鼠的疗效研究[J].解剖科学进展,2008,14(3):277-280. 被引量:5
  • 10Plescis J,Salz W,Xia F,et al.Rational design of shepherdin,a novel anticancer agent[J].Cancer Cell,2005,7(5):457 -468.

二级参考文献28

  • 1张华东,袁守军,陈惠鹏,田增月,韩昌明.Livin mRNA的反义核酸诱导MCF-7乳癌细胞凋亡作用(英文)[J].中国临床药理学与治疗学,2004,9(12):1353-1356. 被引量:14
  • 2王莉萍,沈坤炜,沈镇宙.赫赛汀在乳腺癌新辅助治疗与辅助治疗中的新进展[J].中华肿瘤杂志,2006,28(4):241-243. 被引量:26
  • 3Johnston SR, Leary A. Lapatinib: a novel EGFR/Her2 tyrosine kinase inhibitor for cancer. Drugs Today ( Barc), 2006, 42:441- 453.
  • 4Lackey KE. Lessons from the drug discovery of lapatinib, a dual ErbBl/2 tyrosine kinase inhibitor. Curr Top Med Chem, 2006, 6:435-460.
  • 5Nelson MH, Dolder CR. Lapatinib: a novel dual tyrosine kinase inhibitor with activity in solid tumors. Ann Pharmacother, 2006, 40 : 261-269.
  • 6Rusnak DW, Lackey K, Affleck K, et al. The effects of the novel, reversible epidermal growth factor receptor/ErbB-2 tyrosine kinase inhibitor, GW2016, on the growth of human normal and tumorderived cell lines in vitro and in vivo. Mol Cancer Ther, 2001, 1 : 85-94.
  • 7Xia W, Liu LH, Ho P, et al. Truncated ErbB2 receptor (p95ErbB2) is regulated by heregulin through heterodimer formation with ErbB3 yet remains sensitive to the dual EGFR/ErbB2 kinase inhibitor GW572016. Oncogene, 2004, 23:646-653.
  • 8Xia W, Gerard CM, Liu L, et al. Combining lapatinib (GW572016), a small molecule inhibitor of ErbB1 and ErbB2 tyrosine kinases, with therapeutic anti-ErbB2 antibodies enhances apoptosis of ErbB2-overexpressing breast cancer cells. Oncogene, 2005, 24: 6213-6221.
  • 9Konecny GE, Pegram MD, Venkatesan N, et al. Activity of the dual kinase inhibitor lapatinib (GW572016) against Her-2- overexpressing and trastuzumab-treated breast cancer cells. Cancer Res, 2006, 66:1630-1639.
  • 10Lipton A, Leitzel K, Ali SM, et al. Serum HER-2/neu conversion to positive at the time of disease progression in patients with breast carcinoma on hormone therapy. Cancer, 2005, 104:257-263.

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