对甲基苯甲酸胆甾醇酯的合成及晶体结构

SYNTHESIS AND CRYSTAL STRUCTURE OFCHOLESTERYL pMETHYLBENZOATE

通过对－甲基苯甲酰氯与胆甾醇反应，制得了对甲苯甲酸胆甾醇酯．该化合物晶体呈正交晶系，空间群为Ｐｚ１ｚ１ｚ１，晶胞参数为ａ＝０．９１８０（２）ｎｍ，ｂ＝１．３７３３（３）ｎｍ，ｃ＝２．４５２１（５）ｎｍ，Ｖ＝３．０９１３（１１）ｎｍ３，ｚ＝４，ＤＣ＝１．０８９ｇｃｍ－３，Ｒ＝０．０６１２，ＲＷ＝０．１５９０．

Cholesteryl pMethylbenzoate has been synthesized by the reaction of pmethylbenzoyl chloride with cholesteral in the presence of NEt3. This compound crystallizes in orthorhombic system, space group Pz1z1z1 with the unite cell parameters: a=0.918 0(2) nm, b=1.373 3(3) nm, c=2.452 1(5) nm, v=3.091 3(11) nm3, z=4, DC=1.089 g·cm-3, R=0.061 2, RW=0.159 0.