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Severe acute cholestatic hepatitis of unknown etiology successfully treated with the Chinese herbal medicine Inchinko-to (TJ-135) 被引量:1

Severe acute cholestatic hepatitis of unknown etiology successfully treated with the Chinese herbal medicine Inchinko-to (TJ-135)
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摘要 Severe acute hepatitis of unknown etiology is difficult to treat and often progresses to subacute fulminant hepatitis or late-onset hepatic failure. A 45-year-old wellnourished, healthy man had progressive fatigue and his liver function tests showed severe liver dysfunction. The etiology of sever acute cholestatic hepatitis was unknown. The liver function tests normalized gradually, which excluded high persistent total bilirubin after starting on predonine. A liver biopsy showed chronic active hepatitis with mild f ibrosis (A2, F1). Oral Inchinko-to, a Chinese herbal medicine, at 7.5 g daily was prescribed. The treatment was effective with no adverse effects. We present a successfully treated case and discuss hepatoprotective and choleretic effects of Inchinko-to. Severe acute hepatitis of unknown etiology is difficult to treat and often progresses to subacute fulminant hepatitis or late-onset hepatic failure. A 45-year-old well- nourished, healthy man had progressive fatigue and his liver function tests showed severe liver dysfunction. The etiology of sever acute cholestatic hepatitis was unknown. The liver function tests normalized gradually, which excluded high persistent total bilirubin after starting on predonine. A liver biopsy showed chronic active hepatitis with mild fibrosis (A2, F1). Oral Inchinko-to, a Chinese herbal medicine, at 7.5 g daily was prescribed. The treatment was effective with no adverse effects. We present a successfully treated case and discuss hepatoprotective and choleretic effects of Inchinko-to.
出处 《World Journal of Gastroenterology》 SCIE CAS CSCD 2009年第23期2927-2929,共3页 世界胃肠病学杂志(英文版)
关键词 Acute cholestatic hepatitis ETIOLOGY Inchinko-to Herbal medicine 亚急性 肝炎 治疗 中药 病因 肝功能损害 疲劳试验 高速公路
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  • 1Fujiwara K, Mochida S, Matsui A, Nakayama N, Nagoshi S, Toda G. Fulminant hepatitis and late onset hepatic failure in Japan. Hepatol Res 2008; 38:646-657.
  • 2Aburada M, Sasaki H, Harada M. Pharmacological studies of Gardeniae Fructus II. Contribution of the constituent crude drugs to choleretic activity of "Inchiko-to" in rats. Yakugaku Zasshi 1976; 96:147-153.
  • 3Kobayashi H, Horikoshi K, Yamataka A, Lane GJ, Yamamoto M, Miyano T. Beneficial effect of a traditional herbal medicine (inchin-ko-to) in postoperative biliary atresia patients. Pediatr Surg Int 2001; 17:386-389.
  • 4Iinuma Y, Kubota M, Yagi M, Kanada S, Yamazaki S, Kinoshita Y. Effects of the herbal medicine Inchinko-to on liver function in postoperative patients with biliary atresia- -a pilot study. J Pediatr Surg 2003; 38:1607-1611.
  • 5Kaiho T, Tsuchiya S, Yanagisawa S, Takeuchi O, Togawa A, Okamoto R, Saigusa N, Miyazaki M. Effect of the herbal medicine Inchin-Ko-To for serum bilirubin in hepatectomized patients. Hepatogastroenterology 2008; 55:150-154.
  • 6Arai M, Yokosuka O, Fukai K, Kanda T, Kojima H, Kawai S, Imazeki F, Hirasawa H, Saisho It. A case of severe acute hepatitis of unknown etiology treated with the Chinese herbal medicine Inchinko-to. Hepatol Res 2004; 28:161-165.
  • 7Tang CP, Shiau YT, Huang YH, Tsay SH, Huo TI, Wu JC, Lin HC, Lee SD. Cholestatic jaundice as the predominant presentation in a patient with autoimmune hepatitis. J Chin Med Assoc 2008; 71:45-48.
  • 8Yamamoto M, Ogawa K, Morita M, Fukuda K, Komatsu Y. The herbal medicine Inchin-ko-to inhibits liver cell apoptosis induced by transforming growth factor beta 1. Hepatology 1996; 23:552-559.
  • 9Yamamoto M, Miura N, Ohtake N, Amagaya S, Ishige A, Sasaki H, Komatsu Y, Fukuda K, Ito T, Terasawa K. Genipin, a metabolite derived from the herbal medicine Inchin-ko-to, and suppression of Fas-induced lethal liver apoptosis in mice. Gastroenterology 2000; 118:380-389.
  • 10Takeuchi S, Goto T, Mikami K, Miura K, Ohshima S, Yoneyama K, Sato M, Shibuya T, Watanabe D, Kataoka E, Segawa D, Endo A, Sato W, Yoshino R, Watanabe S. Genipin prevents fulminant hepatic failure resulting in reduction of lethality through the suppression of TNF-alpha production. Hepatol Res 2005; 33:298-305.

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