新损伤严重度评分相关文献统计与评价

Statistical analysis and evaluation of NISS-related articles

目的统计分析自1997年新损伤严重度评分（NISS）被提出以来，在研究及应用领域对其与损伤严重度评分（ISS）等创伤评分系统的比较及NISS的应用。方法以NISS为关键词经PubMed数据库检索1997年12月1日-2008年8月31日与NISS有关的研究文献，对各研究结果进行统计分析。结果共有57项检索结果，其中26项无ISS与NISS相关性比较，其余31项中有24项经比较后显示NISS在预后判断方面不低于ISS，其中样本量介于1000～10000的研究提示NISS优于ISS，样本量〉10000或〈10000的研究中，结果提示NISS优于或等效于ISS。仅有1项研究提示在〈65岁患者，在生存概率方面ISS与NISS相同，但ICU入住率及住院时间ISS优于NISS。结论NISS较ISS在预后判断及计算方面的优越性为我们将NISS取代ISS提供了依据。

Objective To study the application of the New Injury Severity Score（NISS） and its comparison with the Injury Severity Score（ISS） and other trauma severity index,since its presentation in 1997. Methods Articles related to NISS, which published from Dec. 1997 to Aug. 2008 were searched in Pub Med, and the articles were statisticallly analyzed. Results There were 57 articles ,26 of which had no comparison between the two index. In the other 31 articles ,24 articles comparing NISS with ISS （ sometimes including other trauma severity index） showed that NISS was equal to or more accurate than ISS in predicting the outcome. Studies with sample size ranged from 1 000 to 10 000 resulted in NISS-favorable results, whereas studies with sample size larger than 10 000 or smaller than 1 000 showed either NISS-favorable results or no difference between the two groups. Only one research indica- ted that ISS was better than NISS in predicting intensive care unit admission and hospitalization time,and equal to NISS in predicting mortality in patients under the age of 65. Conclusion The superiority of NISS to ISS in the out- come prediction and calculation presents a foundation for us to replace ISS with NISS.