低浓度布比卡因、利多卡因、地卡因用于无痛分娩效果的比较

Comparison of effects of low concentration bupivacaine,lidocaine,and tetracaine solutions in painless childbirth

目的探讨布比卡因、利多卡因与地卡因混合液3种常用局麻药低浓度在持续硬膜外麻醉下镇痛分娩效果的差异。方法将在本院产科137例孕妇随机分为4组,对照组不采取镇痛措施,其余3组分别使用低浓度的布比卡因、利多卡因、地卡因镇痛,比较该3种局麻药对无痛分娩的效果。结果3种低浓度局麻药均可降低分娩产妇的疼痛,镇痛效果有差异。结论分娩镇痛对母婴并无不良影响,3种局麻药均能达到分娩镇痛目的,但0.125%布比卡因镇痛效果最佳,可作为临床首选。

Objective To study the effect of low concentration solutions of bupivaeaine,lidocaine, and tetracaine＋lido-caine mixture used in epidural anesthesia for childbirth pain relief. Methods 137 randomly selected parturient primigravidas in our hospital were reviewed. All cases were divided into four groups. One is control group without any pain relief measures during labor; the others are experimental groups with bupivacaine, tetracaine, lidocaine respectively. Results The three types of low concentration drug used in epidural analgesia can relieve labor pains during vaginal birth. In terms of pain relief effects, significant differences were demonstrated among them. Conclusion Anesthetic pain relief in labor has no significant negative effects on neonates and mothers. The three types of anesthesia drug are able to relieve labor pain. However, 0.125% bubicatine is the best and shall become the first choice.