摘要
目的建立测定飞扬肠胃炎片中有效成分槲皮素含量的方法。方法采用高效液相色谱法测定。以甲醇:0.5%磷酸溶液(50∶50)为流动相,检测波长为360nm,柱温为室温。结果槲皮素在0.058-0.583μg范围内呈良好线性关系,回归方程为Y=3.9810*105X-2.194*102,r=0.9999。表明槲皮素在0.058～0.583μg范围内具有良好的线性关系。结论方法简便,分离效果好,结果准确可靠,可以用于飞扬肠胃炎片的质量控制。
OBJECTIVE To establish a method for determination of quercetin in Feiyang Changweiyan tablets. METHODS The analysis was carried on a column of Hypecrsil BOS2 C18 （250 ×4.6mm, 5μm）with a mobile phase of mathanol- 0.5 % phosphoric acid（50 ： 50）. The detection wavelength was at 360nm. RESULTS The linear regression equation was Y = 3. 9810 ＊ 10^5 X-2.194 ＊ 10^2, r = 0. 9999 for quercetin and The linear range was 0.058 -0. 583μg. CONCLUSION This method is simple and accurate, and suitable for quality control of Feiyang Changweiyan tablet.
出处
《海峡药学》
2009年第6期58-59,共2页
Strait Pharmaceutical Journal
