黄颡鱼腹水病的组织病理研究

Histopathological study of ascites disease in Pseudobagrus fulvidrico

本文应用组织病理学的方法,对患有腹水病的黄颡鱼(Pseudobagrus fulvidrico)的各器官进行观察。结果表明各器官主要组织病理学变化有:鳃小片上皮细胞肿胀、增生、肥大,并有脱落、变性、坏死现象;肾小管上皮细胞出现肿胀,局部肾小管崩解坏死;肾小球结构模糊不清、松散,呈空泡样,部分区域肾小球的血管球肿胀、肾小球坏死;肾间质中可见局灶性坏死,局部区域可见颗粒管型和黑素-巨噬细胞沉着。肝细胞发生明显的水泡变性,部分病鱼肝组织可见局灶性坏死和血管充血。肠胃上皮细胞排列紊乱,并有脱落、变性、坏死现象。脾组织中毛细血管扩张、充血,严重区域破裂出血,形成血斑,部分病鱼脾组织可见弥散性坏死灶。

Various organs of Pseudobagrusfulvidrico contracted with ascites disease were observed using histopathological methods. The results indicated that the main histopathological changes in various organs included swelling, proliferation, hypertrophy of epithelial cells in gill lamellae as well as desquamation, degeneration and necrosis. Epithelial cells of renal tubulus presented the obvious swelling, and partial disintegration and necrosis; The glomerulus whose structure was unclear and loose, had a vacuolar shape. Swollen glomus and necrotic glomerulus were also observed in partial microscopic fields. Local necrotic stove, granular casts as well as melanin-macrophage deposition were found in renal interstitial. Liver cells presented obvious water degeneration, and local necrotic stove and the congestive blood vessel partially in sick fish. Gastrointestinal epithelial cells arranged irregularly, acompanied by epithelial desquamation, degeneration and necrosis. Under the microscope, the expansion and hyperemia of blood capillaries of spleen,even blood stains caused by bleeding could be found. In addation, there were partial diffuse necrosis in the spleen tissue in sick fish.