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俯卧位通气在百草枯中毒百草枯肺中的应用观察 被引量:7

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摘要 目的观察俯卧位机械通气对百草枯中毒百草枯肺患者肺功能残气量(FRC)、气体交换功能及血液动力学的影响。方法8例百草枯中毒百草枯肺患者,均行机械通气治疗,并早期予以俯卧位机械通气治疗,分别于仰卧位和俯卧位后30min行动脉血气分析,随即采用密闭式氦稀释法测定FRC,持续检测动态胸肺顺应性(Csr)以及血液动力学变化;并对2种体位的胸部CT进行比较。结果与仰卧位相比,俯卧位后30min患者FRC从(1.4±0.4)L上升至(1.5±0.3)L(P<0.05),动脉血氧分压(PaO2)显著增加(P<0.01);同时肺泡动脉氧分压差减小、氧合指数上升(P<0.05),Csr差异无统计学意义(P>0.05)。平均动脉压、中心静脉压、心率等血液动力学指标差异无统计学意义(P>0.05)。PaO2与FRC呈正相关关系(r=0.709,P<0.05)。胸部CT显示俯卧位后原背侧渗出性改变有所改善,原腹侧正常肺组织出现渗出性改变。结论俯卧位机械通气可以增加百草枯中毒百草枯肺患者FRC,改善氧合状况,且对血液动力学无明显影响,是该类患者早期支持治疗的重要而有效的手段。
出处 《疑难病杂志》 CAS 2009年第7期422-423,共2页 Chinese Journal of Difficult and Complicated Cases
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参考文献6

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