中央角膜较厚的高眼压症者临床随访观察

Follow clinical observation of ocular hypertension of the central corneal thickness

目的：探讨高眼压症者中央角膜厚度（CCT）与眼压（IOP）的关系,观察CCT在判断高眼压症者是否给予降眼压治疗中的临床价值。方法：对113例（226眼）高眼压症者进行超声角膜厚度测量和非接触眼压计（NCT）测眼压,对校正眼压〈21 mm Hg者52例（104眼）不给予降眼压药物治疗,跟踪观察其眼压、视野、生理杯和视网膜神经纤维层的变化。结果：IOP随CCT呈正相关变化,CCT每增加100μm,IOP将随之增加1.86 mm Hg。对校正眼压〈21 mm Hg者不予以降眼压治疗,跟踪观察12~36个月,只有3例（6眼）出现视野和视神经纤维层改变,发生率为2.66%（6？226）。结论：中央角膜厚度测量可以作为高眼压症与开角型青光眼进行鉴别诊断、以及判断高眼压症能否发展成为青光眼的可靠依据,对高眼压症者要常规进行角膜厚度测量并校正其眼压,校正眼压〈21 mm Hg者,可不用降眼压药物干预。

Objective：To investigate ocular hypertension the relationship between central corneal thickness （CCT） and intraocular pressure （IOP） , observe CCT in the ocular hypertension and determine whether to reduce intraoeular pressure clinical value of the treatment. Methods：113 cases （226 eyes） ocular hypertension who were carried ultrasound measurement of the cornea thickness and the non -contact tonometer （NCT） intraocular pressure measurement, 52 cases （104 eyes） correction of the intraocutar pressure 〈 21mmHg will not give pressure drug treatment, follow - up observation the intraocular pressure, vision and physical up and retinal nerve fiber layer. Results： IOP and CCT were positively correlated with the changes, CCT for each additional 100p.m, IOP will increase 1.86mmHg. Correction of the intraocular pressure 〈 21mmHg will not give the treatment of ocular hypertension, followed observation 12 to 36 months, vision and optic nerve fiber layer changes only 3 cases （6 eyes）, incidence 2.66% （6 / 226）. Conclusions： the Central corneal thickness measurement can be used as ocular hypertension and open - angle glaucoma for the differential diagnosis and judge ocular hypertension whether can be developed into a reliable basis for glaucoma, for those who often should carry out corneal thickness measurement and their correction Intraocular pressure, IOP correction 〈 21mmHg, there is no need for reduce intraocular pressure drugs.