动脉压迫止血器在经股动脉介入术后的临床应用

The clinical utility of domestic artery compressor after percutaneous intervention via femoral artery

目的探讨动脉压迫止血器在经股动脉介入术后的安全性、有效性及临床应用价值。方法402例经股动脉介入检查术后的患者,将手工压迫止血175例作为对照组,用股动脉压迫止血器压迫止血227例作为试验组;另117例冠状动脉介入治疗术后的患者,术后即刻压迫止血的61例患者作为治疗即刻组,术后2 h压迫止血的56例患者作为治疗2 h组。比较止血成功率、止血时间、下肢制动时间、主要并发症发生情况。结果介入检查术后两组止血成功率差异无统计学意义(P>0.05),试验组止血时间、下肢制动时间、血管并发症发生率均明显低于对照组,差异有统计学意义(P<0.05)。介入治疗术后2 h压迫止血组血管并发症明显低于治疗即刻组,差异也有统计学意义(P<0.05)。结论经动脉压迫止血器压迫止血可明显减少止血时间,缩短患者卧床时间,且在介入治疗术后2 h应用可明显减少血管并发症,值得临床推广应用。

Objective To explore efficacy and safety of domestic artery compressor for pereutaneous intervention by femoral approaches. Methods A total of 402 patients after coronary angiography by femoral approaches were randomly divided into two groups, artery compressin group （test group, n = 227） and manual compression group （ control group, n = 175）. In addition, 117 patients after percutaneous intervention （PCI） by artery compressor approaches were randomly divided into two groups. Compressing instantly（control group, n = 61 ） and 2 hours （test group, n = 56） after PCI. The efficacy endpoint（immediate successful hemostasis rate, time to hemostasis and ambulation）and taema- jor complications were evaluated. Results The rates of successful hemostasis were similar between the test group and the control group（P〈0.05）. The time to hemostasis and to ambulation in test group was significantly shorter than that of control group（P〈0.05） ;the rate of major complications was also lower in test group. Conclusion Applica- tion of domestic artery compressor after percutaneous intervention by femoral approaches improves the hemostastic effects and reduces perivascular complications. Furthermore,it is strongly recommended to use it 2 hours after PCI. It is worthwhile for wide clinical utilization.