男性不育患者精子核蛋白组型转换与精子密度及活力分析

The study of the relationship between sperm nucleoprotein transition and sperm density and motility in male infertility

目的探讨男性不育患者精子核蛋白组型转换与精子密度及活力的关系,为男性不育的治疗提供资料。方法精液常规分析后,按精子密度、活力的不同进行分组。分别检测各组精子核蛋白组型转换率。利用t检验对结果进行统计学分析。结果不同精子密度组(<20×106/mL、20×106/mL～40×106/mL、40×106/mL～60×106/mL、≥60×106/mL)精子核蛋白组型转换率分别为:(81.43±10.01)%、(83.30±11.23)%、(79.57±10.49)%、(81.71±9.14)%。不同精子活力组(<10%、10%～30%、30%～50%、50%～70%、≥70%)精子核蛋白组型转换率分别为:(77.86±12.80)%、(79.76±12.22)%、(81.74±9.48)%、(79.45±10.58)%、(84.72±10.25)%。统计学分析结果表明,不同精子密度组与不同精子活力组比较,差异无统计学意义。结论男性不育患者精子核蛋白组型转换与精子密度及活力无关,精子核蛋白组型转换可能是影响男性不育的一个独立性因素。

Objective To explore the relationship between sperm nucleoprotein transition and sperm density and motility,and to provide information for male infertility therapy. Methods After the routine analysis of semen , the specimens were divided into different groups in accordence with the different sperm density and motility. Then the rates of sperm nucleoprotein transition were detected. The statistic analysis was made by means of T test. Results The sperm nucleoprotein transition rate of different sperm density groups（〈20×10^6/mL、20×10^6/mL40×10^6/mL、40×10^6/mL～60×10^6/mL、≥60×10^6/mL） was81.43±10.01）%、（83.30±11.23）%、（79.57±10.49）% and （81.71±9.14）%.And the rate of different sperm motility groups （77.86±12.80）%、（79.76±12.22）%、（81.74±9.48）%、（79.45±10.58）%、（84.72±10.25）%. The results of statistic analysis show that the nu- cleoprotein transition rate of different sperm density groups and motility groups was of no significant difference. Conclusion The sperm nucleoprotein transition rate of male infertility was nothing to do with sperm density and motility.