期刊文献+

雌激素受体α(ERα)与β(ERβ)表达的研究和检测技术新进展及其在疾病预后判断中的应用 被引量:11

下载PDF
导出
摘要 雌激素是一种由内分泌系统产生的类固醇性激素.它在生殖系统、骨组织、心血管、免疫系统及中枢神经系统、内分泌系统中都发挥着重要的作用。乳腺癌、骨质疏松、阿尔茨海默病、绝经后妇女动脉粥样硬化及儿童性早熟的发生等都与雌激素有着密切的关系.
作者 柯江维 段荣
机构地区 江西省儿童医院
出处 《实验与检验医学》 CAS 2009年第3期291-294,共4页 Experimental and Laboratory Medicine
  • 相关文献

参考文献31

二级参考文献112

  • 1Bord S,Horner A,Beavan S,et al.Estrogen receptors alpha and beta are differentially expressed in developing human bone.J Clin Endocrinol Metab,2001,86(5):2309-2341
  • 2Price RH,Butler CA,Webb P,et al.A splice variant of estrogen receptor beta missing exon displays altered subnuclear localization and capacity fortranscriptional activation.Endocrinology,2001,142(5):2039-2049
  • 3Ogawa S,Hosoi T,Shiraki M,et al.Association of estrogen receptor beta gene plolymorphism with bone mineral density.Biochem Biophys Res Commun,2000,269(2):527-541
  • 4Knoblauch R,Garabedian M J.Role for Hsp90-associated cochaperone p23 in estrogen receptor signol transduetion.Mol Cell Biol,1999,19(5):3748-3759
  • 5Liu G,Schwartz JA,Brooks SC.Estrogen receptor protects p53 from deactivation by human double minute 2.Cancer Res,2000,60(7):1810-1814
  • 6Katzenellenbogen BS,Katzenellbogen JM.estrogen receptor transcription and transactivation:Estrogen receptor alpha and estrogen receptor beta:regulation by selective estrogen receptor modulators and importance in breast cancer.Breast Cancer Res,2000,2(5):335-344
  • 7Lau KM,Laspina M,Long J,et al.Expression of estrogen receptor (ER)-alpha and ER-beta in normal and malignant prostatic epithelial cells:regulation by methylation and involvement in growth regulation.Cancer Res,2000,60(12):3175-3182
  • 8Matsuzaki S,Fukaya T,Suzuki T,et al.Oestrogen receptor alpha and beta mRNA expression in human endometrium throughout the menstrual cycle.Mol Hum Reprod,1999,5(6):559-564
  • 9Mowa CN,Iwanaga T.Differential distribution of oestrogen receptor alpha and beta mRNAs in the female reproductive organ of rats as revealed by in siut hybridization.J Endocrinol,2000,165(1):59-66
  • 10Takeyama J,Suzuki T,Inoue S,et al.Expression and cellular localization of estrogen receptor alphar and beta in the human fetus.J Clin Endocrinol Metab,2001,86(5):2258-2262

共引文献88

同被引文献152

引证文献11

二级引证文献31

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部