多普勒组织成像技术测量脉搏波速的真实性和可行性

Validity and feasibility of measurement of pulse wave velocity by Doppler tissue imaging

目的评价多普勒组织成像(DTI)法测量脉搏波速的真实性和可行性。方法行冠脉造影患者50例,测量主动脉两定点距离L,并与体表不同标志做相关性分析。测量脉搏波传递时间(PWT1),脉搏波速(PWV1)=L/PWT1,此40例患者行DTI法测量电-机械时间(EMT)、左室射血前期(PEP)、脉搏波传递时间(PWT2),PWT2=EMT-PEP,PWV2=L/PWT2,两种方法测得PWT1与PWT2,PWV1与PWV2分别行直线相关分析;上述主动脉两定点距离与体表长度间行相关性分析。结果PWT1为(24±9)ms,PWT2为(24±9)ms,二者之间无显著差异,具有显著相关性(r=0.91,P<0.01)。PWV1为(14±5)m/s,PWV2为(14±5)m/s,二者之间无明显差异,亦具有高度相关性(r=0.92,P<0.01),上述主动脉两定点距离与胸骨角至胸骨体下缘长度2倍加1cm的相关系数为0.90,而且这两组数据间无显著性差异。结论DTI法可做为无创测量PWT方法,选用胸骨角至胸骨体下缘长度2倍加1cm做为主动脉段长度估计值测得的PWV值是准确可用的。

AIM： To study the correlation of two measured values of pulse wave time： PWT1 obtained by catheter and PWT2 obtained by Doppler tissue image （DTI） and the correlation of two measured values： aortic root to a point in the abdominal aorta 2 cm below the septum and length of body surface and to estimate the validity and feasibility of pulse wave velocity measurement using DTI . METHODS ： A total 50 patients who had coronary arteriography were included in this study. Length of artery （L） was measured to study the correlation between L and different surface markers. PWV1 was obtained by PWV1 = L/PWT1.Electromechanical time （EMT） and left ventricular pre-ejection period （PEP） were measured by DTI, and PWV2 was obtained by PWT2 = EMT - PEP, PWV2 = L/PWT2. PWT1 and PWT2, PWV1 and PWV2, and the value of distance from aortic root to a point in the abdominal aorta 2 cm below the septum and the value of length of surface were then statistically compared. RESULTS ： PWT1 was （24 ± 9） ms and PWT2 was （24±9） ms, with no significant difference between PWT1 and PWT2. A positive correlation was found between the two （r =0. 91, P 〈0. 01）. PWV1 was （14±5） m/s and PWV2 was （ 14±5） m/s, with no significant difference between PWV1 and PWV2, but a positive correlation was also found between the two （r =0.92, P 〈 0. 01 ）. A positive correlation was found between the value of length of artery and the 1 cm ＋ double values of length from angle of sternum to inferior border of sternum （ r =0.90, P〈0.01）. from the estimated angle of sternum to CONCLUSION： DTI is value of the length of arte inferior border of body of a noninvasive approach to measure PWT and PWV. PWV ry is precise by using 1 cm ＋ double values of length from sternum.