微循环障碍疗法治疗代谢综合征的随机对照试验

Therapeutic effects of treatment of microcirculation disorders in metabolic syndrome

目的观察微循环障碍疗法对代谢综合征(metabolic syndrome,MS)的治疗效果。方法对符合美国NCEP-ATP诊断标准的123例MS患者,随机分为两组,治疗组63例采用微循环障碍疗法,对照组60例采用常规治疗,一个月后进行各组治疗前后的指标自身对照以及两组间比较。结果两组经治疗后腹围、血压、血糖、血脂等各项指标均较治疗前降低,各组间治疗前后自身对比有非常显著性差异(P<0.01);②微循环障碍治疗后,各项指标降幅更为明显,两组间治疗后疗效对比,各项指标均有显著性差异(P<0.05)。结论微循环障碍疗法对MS的治疗较常规治疗有更好的效果,值得进一步研究。

AIM： To investigate the therapeutic effects of treatment of microcirculation disorders on metabolic syndrome （MS）. METHODS： One hundred and twenty three MS patients who fulfilled the diagnostic criteria of the American National Cholesterol Education Program （NCEP） Adult Treatment Panel Ⅲ （ATPⅢ） were enrolled in the study and randomly divided into two groups. Sixty three patients were treated with microcirculation disorder treatment and the other 60 patients were treated with conventional therapy. The indicators of the same patients before and after treatments were compared. We also compared the indicators of the subjects from one group with those of the subjects from the other group, before and after a month of different treatments. RESULTS： 1 ） The indicators, including abdominal circumference, blood pressure, blood sugar and lipids of the patients from the two groups decreased after the treatments. Significant differences were observed in each group when the indicators before treatment were compared with those after treatment （P 〈 0. 01 ）. 2） After the microcirculation disorder treatment, indicators decreased more significantly. When we compared the effects of the two treatments, all indicators showed marked differences （P 〈 0.05）. CONCLUSION： Microcirculation disorder treatment has significantly better therapeutic effects on MS when compared with conventional therapy and deserves further research.