新型防霉剂富马酸二甲酯合成工艺的研究

Studies on the synthesis of dimethyl fumarate

探讨了以顺酐和甲醇为原料、用复配制得的固体酸作催化剂合成富马酸二甲酯的新工艺．主要讨论了原料的配比和分批投料、反应温度分段控制及各段反应时间对产品收率的影响．

The authors deal with the synthesis of dimethyl fumarate from maleic anhydride and methanol,using mixingsolid acid catalyst,which can increase purity to 98% and yields over 99% .Besides,some factors which affect yields are also discussed.