直肠癌肝转移5例诊断与治疗分析
摘要
目的:探讨直肠癌肝转移的外科治疗方法及其对预后的影响。方法:本组5例直肠癌肝转移患者接受原发灶根治术以及肝转移灶切除术。结果:随着技术的进步,对于直肠癌肝转移患者,手术的适应证得到了很大拓展。
二级参考文献21
-
1Micev M, Micev-Cosic M, Todorovic V, et al. Histopathology of residual rectal carcinoma following preoperative radiochemotherapy[J]. Acta Chir Iugosl,2004, 51 (2) :99 - 108.
-
2Gerard JP, Chapet O, Nemoz C, et al. Preoperative concurrent chemoradiotherapy in locally advanced rectal cancer with high-dose radiation and oxaliplatin-containing regimen: the Lyon R0-04 phase Ⅱ triM[J]. J Clin Oncol, 2003,21 (6) :1119 -1124.
-
3Buie WD, MacLean AR, Attard JA, et al. Neoadjuvant chemoradiation increases the risk of pelvic sepsis after radical excision of rectal cancer[ J ]. Dis Colon Rectum,2005 , 48 (10) :1868 - 1874.
-
4Turner Ⅱ, Russell GB, Blackstock AW, et al. Impact of neoadjuvant therapy on postoperative complications in patients undergoing resection for rectal adenocarcinoma [ J ]. Am Surg,2004,70(12) :1045 - 1049.
-
5Schulze-Bergkamen H, Krammer PH. Apoptosis in cancer - - implications for the-rapy [ J ] . Semin Oncol, 2004,31 (1):90-119.
-
6Fulda S, Debatin KM. Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy [J].Oncogene, 2006 , 25(34) :4798 -4811.
-
7Kostanova-Poliakova D, Sabova L. Anti-apoptotic proteinstargets for chemosen-sitization of tumor cells and cancer treatment[J]. Neoplasma, 2005,52(6) :441 -449.
-
8Sturm I, Rau B, Schlag PM, et al. Genetic dissection of apoptosis and cell cycle control in response of colorectal cancer treated with preoperative radiochemotherapy [ J ]. B-MC Cancer, 2006,10(6) :124.
-
9Scholzen T, Gerdes J. The ki-67 protein: from the known and the unknown[ J]. J Cell Physiol, 2000, 182 (3) : 311 -322.
-
10Allegra C J, Paik S, Colangelo LH, et al. Prognostic value of thymidylate synthase, ki-67, and p53 in patients with Dukes' B and C colon cancer: a National Cancer Insti tute-National Surgical Adjuvant Breast and Bowel Project collaborative study[J]. J Clin Oncol, 2003,21 (2) :241 -250.
共引文献20
-
1周建平.老年胃肠癌病人围手术期化疗[J].中国实用外科杂志,2009,29(2):127-130.
-
2陈启,姚玉民,张莹,许俊龙.新辅助化疗后乳腺癌组织中survivin和Ki-67的表达及意义[J].中国普通外科杂志,2009,18(5):438-441. 被引量:4
-
3张国成.青年人直肠癌45例临床分析[J].河南科技大学学报(医学版),2009,27(3):199-200.
-
4朱其勇,刘陶文.新辅助化疗对大肠癌免疫功能的影响[J].检验医学与临床,2010,7(10):991-992.
-
5朱其勇,刘陶文.新辅助化疗对大肠癌免疫功能的影响[J].中国医药指南,2010,8(18):60-62. 被引量:1
-
6卢昕,郑启昌.靶向survivin的siRNA诱导肝癌细胞化疗敏感性的研究[J].中国普通外科杂志,2010,19(8):875-880. 被引量:7
-
7倪敏.CapeOX方案新辅助化疗结合手术治疗不可切除的结直肠癌肝转移[J].中国普通外科杂志,2011,20(4):347-351. 被引量:6
-
8邱成志,吴友谊,王春晓.Ⅲ期结直肠癌淋巴结转移比率与预后的关系[J].中国普通外科杂志,2011,20(10):1025-1028. 被引量:3
-
9黄金亮,王继见.结直肠癌新辅助化疗的研究进展[J].中外医疗,2012,31(6):188-189. 被引量:8
-
10黄俊明,伍宏章,李铮宇,邝永龙.新辅助化疗治疗中晚期直肠癌患者的临床效果观察[J].浙江临床医学,2012,14(3):310-311. 被引量:3
-
1陈明.直肠癌肝转移72例诊治体会[J].现代医药卫生,2008,24(2):244-244.
-
2黄庆先,宋占文,贾秀梅,孟珂伟,周先亭.腹腔镜直肠癌根治并同时性肝转移癌切除二例分析[J].中华普通外科杂志,2006,21(12):900-900. 被引量:5
-
3周祝谦,陈文昌,刘晶云.结肠及直肠癌肝转移临床介入治疗分析[J].山东医药,2002,42(9):32-32. 被引量:1
-
4张庆旺,宋步需,王振全,赵金良,吴孟超,赵建武,张利辉,崔忠.结、直肠癌肝转移的外科治疗[J].中华外科杂志,1995,33(3):161-163. 被引量:11
-
5王竹平.直肠癌肝转移误诊的教训[J].腹部外科,1989,2(4):180-181.
-
6Sile.,W.,林言箴.结,直肠癌肝转移作肝切除术的现况[J].国外学者来访报告,1989,9(1):15-17.
-
7王学浩.结、直肠癌肝转移的诊治特点[J].中国实用外科杂志,1995,15(5):268-269. 被引量:14
-
8平世民,关丽霞,王礼.重组人血管内皮抑素联合化疗治疗直肠癌肝转移的疗效分析[J].基层医学论坛,2013,17(S1):21-22.
-
9任黎,翟升永,钟芸诗,韦烨,许剑民.直肠癌肝转移的综合治疗进展[J].中华外科杂志,2010,48(21):1613-1615.
-
10张民献.结直肠癌肝转移手术治疗分析[J].当代医学,2011,17(15):88-88. 被引量:2