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葡萄球菌属158株耐药性分析

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摘要 目的:探讨基层医院葡萄球菌的耐药现状及其对9种抗菌药物的耐药性,指导临床合理选用抗菌药物。方法:2005年1月至2008年12月监利县人民医院分离葡萄球菌属158株,采用Kirty-Bauer纸片扩散法选用9种抗菌药物进行药敏试验,耐甲氧西林葡萄球菌(MRS)检测,按美国临床实验室标准化委员会(NCCLS)1999年标准判断结果。结果:近4年分离的葡萄球菌158株,主要来源于血液和脓性标本,分别占34.2%、32.3%,耐甲氧西林金黄色葡萄球菌(MRSA)检出率为24.1%;耐甲氧西林凝固酶阴性葡萄球菌(MRCNS)检出率为58.0%;其在临床病区分布中居前3位科室是新生儿病房、神经外科、门诊外科;MRSA和MRCNS对9种抗菌药物的耐药率除万古霉素耐药率为0%外,其它抗菌药物均明显高于甲氧西林敏感葡萄球菌(MSS)。结论:MRSA和MRCNS检出率不断升高,对抗菌药物呈多重耐药,治疗此类细菌感染宜参考细菌药敏结果,合理选用抗菌药物。
出处 《长江大学学报(自科版)(下旬)》 CAS 2009年第2期63-64,66,共3页 Journal of Yangtze University
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