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活化小胶质细胞在新生鼠缺氧缺血性脑损伤中的动态变化 被引量：2

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作者 冯雪 刘晓红 孙玲玲
机构地区 深圳市儿童医院新生儿科
出处 《公共卫生与预防医学》 2009年第3期86-87,共2页 Journal of Public Health and Preventive Medicine
基金 深圳市科技计划资助项目(200802061)
关键词 缺氧缺血性脑损伤 小胶质细胞 动态变化 活化 新生鼠 HIBD damage 病理生理过程
分类号 R722.12 [医药卫生—儿科] R743.31 [医药卫生—神经病学与精神病学]
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参考文献8

  • 1夏斌,姚裕家,陈娟,程开健.新生鼠实验性缺氧缺血性脑损伤ER-α、IGF-1R的表达及双重表达[J].四川大学学报（医学版）,2004,35(5):647-649. 被引量：3
  • 2E1 Khoury J, Toft M, Hickman SE, et, al Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimerlike disease [J]. Nat Med,2007,13 (4) :432 - 438.
  • 3Lai AY, Todd KG. Microglia in cerebral ischemia: molecular actions and interactions [J]. Can J Physiol Pharmacol,2006,84 ( 1 ) : 49 - 59.
  • 4Farkas E, Donka G, de-Vos R-A, et, al. Experimental cerebral hypoperfusion induces white matter injury and microglial activation in the rat brain [J]. Acta-Neuropathol-( Berl), 2004,108 ( 1 ) : 57 - 64.
  • 5Abraham H, Lazar G Early microglial reaction following mild forebrain ischemia induced by common carotid artery occlusion in rats [J]. Brain-Res, 2000,862 ( 1 - 2 ) : 63 - 73.
  • 6Meeuwsen S, Bsibsi M, Persoon Deen C, et al. Cultured human adult microglia from different donors display stable cytokine, chemokine and growth factor gene profiles but respond differently to a pro-inflammatory stimulus [J]. Neuroimmunomodulation, 2005,12 (4) :235 -245.
  • 7Schilling M, Besselmann M, Leonhard C. Microglial activation precedes and predominates over macrophage infiltration in transient focal cerebral ischemia:a study in green fluorescent protein transgenic bone marrow chimeric mice[J].Exp-Neurol,2003,183( 1 ) : 25 -33.
  • 8Sanchez Moreno C, Dashe JF, Scott T, et, al. Decreased levels of plasma vitamin C and increased concentrations of inflammatory and oxidative stress markers after stroke[J]. Stroke ,2004,35 ( 1 ) : 163 - 168.

二级参考文献7

  • 1Walton M, Connor B, Lawlor P, et al. Neuronal death and survival in two models of hypoxic-ischemic brain damage. Brain Res Rev, 1999;29(2 3):137.
  • 2Butler JA, Kallo I, Sjoberg M, et al. Evidence for extensive distribution of oestrogen receptor α immunoreactivity in the cerebral cortex of adult rats. J Neuroendocrinology,1999;11(5):325.
  • 3Garcia-segura LM, Wozniak A, Azcoitia L, et al. Aromatase expression by astrocytes after brain injury: implications for local estrogen formation in brain repair. Neuroscience, 1999;89(2):567.
  • 4Beilharz EJ, Russo VC, Butler G, et al. Coordinated and cellular specific induction of the components of the IGF/IGFbp axis in the rat brain following hypoxic-ischemic injury. Mol Brain Res, 1998; 59(2):119.
  • 5Cardona-Gómez GP, Doncarlos L, Garcia-Segura LM. Insulin-like growth factor 1 receptors and estrogen receptors co-localize in female rat brain. Neuroscience, 2000;99(4):751.
  • 6Garcia-Segura LM, Naftolin F, Hutchison JB, et al. The role of astroglia in estrogen regulation of synaptic plasticity and brain repair. J Neurobiol, 1999;40(4):574.
  • 7Cardona-Gómez GP, Mendez P, DonCarlos LL , et al. Interactions of estrogens and insulin-like growth factor-1 in the brain: implications for neuroprotection. Brain Res Rev,2001;37(1-3):320.

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公共卫生与预防医学
2009年 第3期

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