锰过氧化氢酶模拟物的合成、表征及催化活性

Synthesis,Characterization and Activity of Manganese-CAT

为探讨过氧化氢酶(CAT)的催化机理,并对其进行应用体系的基础研究,利用二价锰盐与N,N,N-三(2-苯并咪唑甲基)胺(NTB)反应,制备得到了配合物[Mn(NTB)Cl]Cl.2H2O()和[Mn(NTB)(NO3)](NO3).3H2O().利用元素分析、电导率、NMR、IR和UV-Vis对锰配合物进行了表征.测试了MnCAT以及它们与FeCAT组成的二元体系对H2O2歧化反应的催化活性.结果表明:锰的2种配合物对H2O2歧化反应没有催化活性,而二元体系中锰配合物的存在可以明显提高FeCAT对H2O2歧化反应的催化活性.

To study the catalytic mechanism and the basic application system of catalase （CAT）, two Mn complexes[Mn （NTB）Cl]Cl·2H2O（Ⅰ） and [Mn（NTB）（NO3）] （NO3）·2H2O （Ⅱ） were synthesized by the reaction of N,N,N-tris （2-benzimidazolmethyl） amine （NTB） with Mn （Ⅱ） salts in alcohol. The complexes have been characterized by elemental analysis, conductivity measurements, NMR, IR and UV-Vis. The results show that the MnCAT Ⅰ and Ⅱhave no catalytic activity for the disproportionation of H2O2, however, they can increase the catalytic activity of FeCAT in the binary system.