北京军区新兵人群丁型肝炎病毒感染血清流行病学调查

Seroepidemiological Survey of Hepatitis D Virus Infection in New Military Recruits

目的了解入伍新兵人群中丁型肝炎病毒(HDV)IgM和IgG抗体的流行分布情况,为今后预防工作提供科学依据。方法采用血清流行病学调查方法,利用酶联免疫吸附试验(ELISA)技术,对北京军区近5年来自12个省市的444名入伍新兵血清进行HDVIgM和IgG抗体检测,统计分析其阳性率。结果发现各年间入伍新兵血清HDVIgM、IgG均未检出;对2006、2007年入伍的9169新兵中筛查出的20名HBsAg阳性标本进行HDVIgM、IgG检测,均为阴性。结论该军区入伍新兵人群中HDV感染概率低,危害小。新兵入伍期间,采取加强检疫、乙肝疫苗接种和健康教育等有效预防措施。

[ Objective ] To investigate the epidemic distribution of the anti-hepatitis D Virus （ HDV ） IgM and IgG in the population of new military recruits so as to provide scientific evidence for preventive measures. [ Methods] Enzyme-Linked ImmunoSorbent Assay （ ELISA} was applied in a seroepidemiological survey to test the presence of the anti-HDV IgM and IgG in serum samples from 444 personnel recruited from 12 provinces （cities） in last 5 years, and the positive rate was statistically analyzed. [ Results] There was no positive detection for anti-HDV IgM and IgG in the whole population tested. 20 HBsAg positive samples screened from 9169 recruited personnel during 2006, 2007 period were negative to anti-HDV IgM and IgG test. [ Conclusion] HDV infection probability and potential hazard are low in this population. Quarantine inspection, vaccination and health education etc should be strengthened for the new recruits to prevent Hepatitis D.