加强的全肠外营养支持应用于恶性梗阻性黄疸术后患者的效果

Effect of application of enhanced total parenteral nutrition support to patients after accepting surgery operation for malignant obstructive jaundice

目的探讨将加强全肠外营养支持应用于恶性梗阻性黄疸术后患者的效果。方法将72例术前体能得分≤4分的恶性梗阻性黄疸患者随机分为加强的全肠外营养组和对照组各36例。加强组从术前3d起即给予全肠外营养（TPN），对照组从手术后1d开始给予TPN。观察两组血清总蛋白、白蛋白、前白蛋白、转铁蛋白水平，以及术后肛门排气时间、并发症发生率和术后住院天数。结果术后第3、12天时加强组的各项指标均明显高于对照组，肛门排气时间两组差异无统计学意义，加强组的并发症发生率和术后住院天数均较对照组少。结论从术前3d即开始对恶性梗阻性黄疸患者给予TPN，有助于促进患者恢复、减少并发症和住院天数。

Objective To investigate the effect of enhanced total parenteral nutrition support to patients after accepting surgery operation for malignant obstructive jaundice, Methods Randomly, 72 cases of patients with malignant obstructive jaundice having a body capacity score of ≤4 before the operation were divided into two groups, i. e. , the enhanced total parenteral nutrition group of 36 patients, and the control group of 36 patients. For the enhanced total parenteral nutrition group, total parenteral nutrition （TPN） had been given from three days before the operation, and for the control group, TPN was given from 1 day after the operation. The following items were observed, including serum total proteins, albumin level, pre-albumin level, transferrin level, as well as the time for exhausting by anus after the operation, the occurrence rate of complications, and the days for staying in hospital after the operation. Results The observed index of the enhanced group at the third day and the 12th day are all higher than those of the control group. The time for anus exhausting between the two groups did not show a significance in statistics. And the occurrence rate of complications and the days for staying in hospital after the operation in the enhanced group were less than those of the control group. Conclusions Giving TPN to the patients with malignant obstructive jaundice three days before the operation, will help the patients recover and reduce complications and days for staying in hospital.