期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

T波电交替及其临床意义

T Wave Alternans and Its Clinical Significance
下载PDF
导出
摘要 T波电交替(T wave alternans,TWA)是指在规整的心律时,体表心电图上T波形态、极性和振幅的逐搏交替变化。目前大量研究认为T波电交替是人类及动物缺血心肌发生室速、室颤的标志,是预测发生恶性室性心律失常及猝死的有力预测指标。现就T波电交替的溯源与发展、发生机制、影响因素及临床意义等进行综述。 T wave alternans（TWA） is referred to the gradually alternated changes of T wave in amplitude of vibration and shape on ECG during regular heart rhythm. Recently studies considered TWA as and marker for ventricular tachycardia and ventricular fibrillation in ischemic cardiac muscle. TWA is also an indicator of predicting the malignant arrhythmia and sudden death. This article reviewed the genesis, development, mechanism and clinical significance of TWA.
作者 王晓霞 黄织春
机构地区 内蒙古医学院 内蒙古医学院附属医院心内科CCU
出处 《内蒙古医学杂志》 2009年第5期587-592,共6页 Inner Mongolia Medical Journal
基金 内蒙古医学院重大科研课题(NY2006ZD007)
关键词 T波电交替 恶性室性心律失常 临床意义 T wave alternans（TWA） Malignant arrhythmia Clinical significance
分类号 R540.41 [医药卫生—心血管疾病]
  • 相关文献

参考文献27

  • 1Walker WL, Rosenbaum DS. Repolarization alternans: implications for the mechanism and prevention of sudden cardiac death[J].Cardiovasc Res, 2003, 57(3):599 - 614.
  • 2Schwartz PJ, Malliani A. Electrical alternation of the T - wave: clinical and experimental evidence of its relationship with the sympathetic nervous system end with the long Q-T syndrome[J ]. Am Heart J, 1975, 89:45.
  • 3Verrier RL, Nearing BD. Modified moving average analysis of T - wave alternans to predict ventricular fibrillation with high accuracy [J] .J Appl Physiol, 2002, 92:541.
  • 4Pastore JM, Rosenbaum DS. Role of structural barriers in the mechanism of alternans - induced reentry[J].Circ Res, 2000, 87 (12):1 157.
  • 5Goldhaber JI, Xie LH, Duong, et al. Action potential duration restitution and aherrnans in rabbit ventricular myocytes: the key role of intracellular calcium cycling[J]. Circ Res, 2005, 96(4): 459.
  • 6Wilson LD, Wan X, Rosenbaum DS. Cellular alternans: a mechanism linking calcium cycling proteins to cardiac arrhythmogenesis [J].Ann N Y Acad Sci, 2006,1 080(10):216.
  • 7Klingenheben T, Gronefeld G, Li YG, et al. Effect of metoprol and D, 1- sotalol on microvolt-level T- wave alternans [ J ]. J Am Coll Cardiol, 2001, 38(7) : 2 013.
  • 8Tanno K, Kobayashi Y, Adachi T, et al.Onset heart rate and microvolt T - wave alternans during atrial pacing[ J ]. Am J Cardiol, 2000, 86(8) :877- 880.
  • 9Rashba EJ, Osman AF, Macmurdy K, et al. Influence of QRS duration on the prognostic value of T wave alternans[J]. J Cardiovasc Electrophysiol, 2002, 13(8) : 770 - 775.
  • 10Bloomfield DM, Steinman RC, Namerow PB, et al. Microvolt T -wave alternens distinguishes between patients likely and patients not likely to benefit from implanted cardiac defibrillator therapy: a solution to the Multieenter Automatic Defibrillator Implantation Trial ( MADIT ) Ⅱ conundrum [ J ]. Circulation, 2004,110(14):1 885 - 1 889.

二级参考文献1

共引文献3

内蒙古医学杂志
2009年 第5期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部