磁共振表面弥散系数及灌注成像在脑梗死中脑组织缺血状态的诊断价值

The Value of Apparent Diffusion Coefficient Mapping and Perfusion-Weighted Imaging for the Diagnosis of Ischemic Tissues in Cerebral Infarction

目的探讨磁共振表面弥散系数(ADC)值、灌注成像(PWI)对腔隙性脑梗死和较大面积脑梗死的诊断价值。方法对40例不同时期脑梗死患者进行80人次MRI检查,采用常规MRI检查,T1WI、T2WI和T2FLAIR,以及DWI、PWI等,使用工作站Funtiontool专业图像后处理软件包进行图像分析。结果发现腔隙性脑梗死及较大面积脑梗死病灶的ADC值在不同时期发生类似变化,PWI在较大面积脑梗死诊断中具有明显优势,而在腔隙性脑梗死中未发现明显的缺血半暗带。结论对脑缺血病灶,ADC值和PWI均可量化缺血程度,各具优势,二者结合应用对于临床治疗及评估预后均具有重要作用。

Objective To study the value of apparent diffusion coefficient and perfusion weighted imaging in diagnoising lacunar infarction and cerebral infaetion. Methods 80 work-ups of 40 patients in various stages of cerebral infaction were imaged with MRI, T1 WI, T2 WI, FLAIR, DWI and PWI. At the same time, workstation＇s Funtiontool professional image post-processing software package was adopted for image analysis. Results The ADC value of lesions of lacunar infarction and cerebral lesions of larger area underwent similar changes at different points. PWI showed obvious advantages in the diagnosis of cerebral infarction of larger area, while patent lack of ischemic penumbra was not found in lacunar infarc- tion. Conclusion In terms of lesions of cerebral ischemia, both ADC value and PWI can quantify the level of ischemia with their respective advantages. The application of the two measurements combined would play an important role in clinical treatment and prognosis.