ADC值对肝脏良恶性肿瘤鉴别诊断的研究

The application of ADC values to differentiate benign and malignant hepatic tumor

目的探讨MR扩散成像及ADC值对肝脏良恶性肿瘤的诊断价值。方法肝脏占位性病变96例均进行MRI常规扫描及DWI,测出ADC值。以恶性肿瘤ADC值单侧上界的95%可信区间为界限判断肿瘤的良恶性,进行分析。结果肝囊肿和血管瘤ADC值均明显高于原发性肝癌、转移瘤(P<0.01),以ADC=1.83×10-3mm2/s为标准,大于1.83为良性,小于1.83为恶性。结论MR扩散成像及ADC值的应用大大提高了MRI对肝脏恶性肿瘤的诊断和鉴别诊断能力。

Objective To evaluate the application of MR DWI and ADC values in the hepatic malignant tumor. Methods Ninty-six patients with hepatic lesions were examined by MR. All of DWI and conventional MRI were performed and the ADC values were measured. One side upper limit of 95% permissible interval of ADC was adopted as the pointed to differentiate the malignant and benign lesions. Results The ADC values of malignant lesions were significant lower than that of benign lesions （P 〈 0.01 ）. The ADC ≤ 1.83 were malignant leisions and the ADC 〉 1.83 were benign. Conclusion The application of DWI and ADC value can greatly improve the ability to differentiate benign from malignant hepatic lesions.