局部热疗联合全身化疗治疗晚期非小细胞肺癌的系统评价

Local Hyperthermia Combined With Chemotherapy for Advance Non-Small Cell Lung Cancer:A Systematic Review

背景与目的肿瘤热疗与化疗具有协同作用，应用越来越广泛。本文系统评价局部热疗联合全身化疗治疗晚期非小细胞肺癌的疗效和副作用。 方法全面搜索热疗联合化疗对比单纯化疗治疗晚期非小细胞肺癌的随机对照试验，根据Cochrane Handbook4．2．6质量评价标准进行评价，用RevMan5．0进行统计学分析。

Background and objective There is a synergistic action when chemotherapy is combined with hyperthermia in the treatment of cancers. The objective of this study was to determine the ef- fectiveness and adverse effects of patients with NSCLC treated with local hyperthermia combined with chemotherapy versus chemotherapy alone. Methods This is a systematic review of randomized controlled trials. The literature search, study selection, data collection and quality assessment of studies were undertaken according to the Cochrane Handbook 4.2.6 and the statistic analysis were calculated using RevManS.0 software application.