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全身化疗和支气管动脉灌注联合CIK过继免疫治疗Ⅲ期非小细胞肺癌的临床研究 被引量:2

全身化疗和支气管动脉灌注联合CIK过继免疫治疗Ⅲ期非小细胞肺癌的临床研究
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摘要 背景与目的比较支气管动脉灌注化疗、全身静脉化疗和支气管动脉灌注联合CIK细胞过继免疫治疗Ⅲ期非小细胞肺癌,探讨支气管动脉灌注联合CIK细胞过继免疫治疗中晚期非小细胞肺癌的可行性。 Background and objective To compare therapeutic effect among bronchial arterial infusion (BAI), traditional vein chemotherapy and BAI plus cytokine-induced killer cells (CIK), for late NSCLC. Methods A total of 120 patients were enrolled in this study, dividing random into three groups: bronchial arterial infusion (BAI), traditional vein chemotherapy and BAI plus cytokine- induced killer cells (CIK). Clinical effects and side effects were estimated after two period of therapy.
出处 《中国肺癌杂志》 CAS 2009年第6期493-494,共2页 Chinese Journal of Lung Cancer
基金 云南省科技强省基金(项目编号2007C009Z) 云南省教育厅基金(项目编号06y113C)资助
关键词 非小细胞肺癌 支气管动脉灌注 CIK细胞 化疗 Non-small cell lung cancer Bronchial arterial infusion Cytokine-induced killer cells Chemotherapy
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同被引文献11

  • 1Jiang Jingting, Wu Changping, Lu Binfeng. Cytokine-induced killer cells promote antitumor immunity[J]. Journal of Transla- tion Medicine, 2013,11:83.
  • 2Metha BA, Schmidh-Wolf, Weissman IL, et al. Two path ways of exocytosis of cytoplasmic granule contents and target cell kill- ing by cytokine-induced CD3+ CD56 + killer cells [ J ]. Blood, 1995,86 ( 9 ) : 3493 -3499.
  • 3Zhang Jinying, Zhu Lingjun, Wei Juan, et al. The effect of cy- tokine-induced killer cells for treatment of patients with solid tumors: a clinical retrospective study [ J ]. J Cancer Res Clin Onclo, 2012,138 : 1057-1062.
  • 4Huang ZM, Li W, Li S, et al. Cytokine-induced killer cells in combination with transcatheter arterial chemoembolization and radiofrequency ablation for hepatocellular carcinoma patients [ J]. J Immunother,2013,36(5) :287-293.
  • 5Liao W, Lin JX, Leonard WJ. Interleukin-2 at the crossroads of effector responses, tolerance, and immunotherapy [ J ]. Im- munity,2013,38 ( 1 ) : 13-25.
  • 6James AM, Hsu HT, Dongre P, et al. Rapid activation recep- tor- or IL-2-induced iytic granule convergence in human natural killer cells requires Sre, but not downstream signaling [ J ]. Blood, 2013,121 (14) :2627-2637.
  • 7袁香庆,崔传亮,斯璐,盛锡楠,廉红云,迟志宏,郭军.化疗联合CIK细胞回输治疗转移性肾细胞癌Ⅱ期临床研究[J].肿瘤学杂志,2008,14(5):362-365. 被引量:19
  • 8薛明,杨谛,单风平.白介素-2及干扰素-γ对人成骨细胞增殖的影响[J].微生物学杂志,2009,29(4):59-61. 被引量:2
  • 9王士勇,杜微丽,张晖,乌兰图雅,张远,何英,杨云锋,刘飒,张哲,王佳玲.重组人纤维连接蛋白诱导的CIK细胞的生物学特性和对肺癌细胞株杀伤活性的体外研究[J].中国肺癌杂志,2010,13(4):277-281. 被引量:27
  • 10樊永丽,赵华,于津浦,李慧,任宝柱,曹水,刘亮,李润美,张乃宁,安秀梅,任秀宝.胃癌患者术后化疗联合CIK免疫治疗的临床疗效[J].中国肿瘤生物治疗杂志,2012,19(2):168-174. 被引量:32

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