Methylseleninic Acid on The Apoptosis Induction and Invasion Inhibition in Human High-Meta-static Large Cell Lung Cancer Cell Line L9981

Background and Objective Lung cancer, which has been proved to have fastest increasing rate of morbidity and mortality, appears to be one of the most dangerous malignant tumor that

Background and Objective Lung cancer, which has been proved to have fastest increasing rate of morbidity and mortality, appears to be one of the most dangerous malignant tumor that is threatening human being＇s health and lives. For recent 20 years, although researchers have dedicated themselves to the basic studies and clinical therapies on lung cancer, and managed to have many inspiring progresses, the total cure rate on lung cancer still tragically remains at about 15%. Therefore, searching for new anti-lung-cancer drugs, especially the one with high anti-cancer efficiency and low toxicity attracts increasingly more researchers. Selenium, as an essential element, plays an important role in physiological function as well as cancer prevention and therapy. Methylseleninic acid （MSA） is a kind of artificially developed selenium compound, which appears to be the best candidate for cancer prevention and/or therapy,