摘要
采用干法灰化,电感耦合等离子体-原子发射光谱法(ICP-AES)测定正常大鼠胃内硫糖铝中的铝量。结果表明,最佳分析波长为396.153nm,检出限为8ng·mL-1,各组内相对标准偏差均小于0.81%,组间相对标准偏差均小于13.4%,铝的回收率在96.0%—99.5%之间,表明ICP-AES测定大鼠胃内硫糖铝中铝的精密度、准确度良好,满足生物样品分析要求。大鼠灌服硫糖铝6h后胃内的铝基本排空,与正常胃排空时间一致,表明硫糖铝中的铝对正常胃粘膜无粘附作用。
The residue level of aluminium in gastric ulcer was determined by ICP-AES under the wavelength of 396. 153nm. The detection limit is 8ng · mL^-1. The RSD is in the range of 0.81%- 13. 4%,and the recovery is in the range of 96.0%-99.5%. The method meets the requisition of aluminium detection. Six hours after the intragastric administration of sucralfate, aluminium was nearly evacuated from the stomach,it indicated that aluminium of sucralfate had no adhersion to the gastric mucosa.
出处
《光谱实验室》
CAS
CSCD
北大核心
2009年第3期574-577,共4页
Chinese Journal of Spectroscopy Laboratory
