急性脑卒中患者入院血压与残疾及死亡关系

Relationship between admission blood pressure and in-hospital disablity and death among acute stroke inpatients

目的探讨急性脑卒中患者入院血压水平与住院期间发生死亡、残疾的关系。方法对2003年1月-2005年12月间内蒙古通辽市6家医院的3938例脑卒中患者,进行血压测量及其他基线资料的收集,采用χ2检验进行统计分析。结果缺血性脑卒中的残疾发生率(41.3%)高于出血性脑卒中(34.3%)(P<0.05);出血性脑卒中的病死率(5.9%)高于缺血性脑卒中(1.8%)(P<0.05);缺血性脑卒中在不同收缩压和舒张压水平下,其残疾率和病死率差异无统计学意义(P>0.05);而出血性脑卒中的残疾率随着收缩压和舒张压的升高而增高,病死率在不同血压水平下差异有统计学意义(P<0.01);在收缩压≥180mmHg和舒张压≥110mmHg时病死率最高。结论急性出血性脑卒中患者入院血压与住院期间残疾及病死相关。

Objective To examine the association between admission blood pressure （BP） and disability and death among acute stroke inpatients. Methods A total of 3938 acute stroke inpatients from six hospitals were included in the study. Baseline data including BP measurement and clinical outcomes during hospitalization were collected from January,2003 to December,2005. The analysis was conducted with χ2 test. Results The disability rate was higher for those with acute ischemic stroke （41.3%） compared with acute hemorrhagic stroke （34.4%）. The case-fatality rate was higher in acute hemorrhagic stroke（5. 9% ） than that of in acute ischemic stroke（ 1.8% ）. There were no significant difference in disability rate and case-fatality rate among ischemic stroke inpatients with different BP levels （ P 〉 0. 05 ）. However, disability rate was increased with BP level and there was a significant difference in case-fatality rate among hemorrhagic stroke inpatients with different BP levels （P 〈 0. 05 ）. Case-fatality rate was the highest in patients with SBP ≥180mmHg and DBP ≥ 110mmHg. Conclusion Admission BP was significantly and positively associated with disability and death among acute hemorrhagic stroke inpatients.