临床手术追踪数据的多元方差分析

The Multivariate Analysis of Variance in Processing Clinical Surgery Longitudinal Data

目的探讨多元方差分析在处理临床手术追踪数据中的应用,以评估不同手术方式对改善患者症状和生活质量的影响,从而得出更可靠、更科学的专业结论。方法通过健康调查简表(SF-36)对38例慢性鼻窦炎鼻息肉患者术前、术后1个月和术后6个月进行随访调查,以总体健康得分为评价指标,并运用SAS 9.1软件进行分析,比较采取不同范围的手术方式对患者进行治疗的效果。结果经手术治疗,患者术后1个月总体健康状况开始出现好转(P<0.01)。而不同范围的手术方式对患者症状和QOL状态影响的差别无统计学意义(P>0.05)。结论术后1个月患者症状基本改善,而不同范围手术对病变范围相同或相似患者症状和生活质量的改善基本相同,建议选用改良型鼻内镜手术。

Objective Discuss the application of the multivariate analysis of variance to processing the clinical surgery longitudinal data,to evaluate the influence of the different kinds of surgery in improving the symptom and the quality of life,in order to reach a better and more scientific professional conclusion. Methods Do follow-up survey to the 38 chronic nasosinusitis rhino polypus patients by SF-36 on the before of the surgery,the fwst and the sixth month after the surgery,be the totality health score as the evaluate index, then analyze with the SAS9. 1, compare the therapy effect of different kinds of surgery. Results By the surgery, the totality health status of the patients become better one month after the surgery, and the influence of the different kinds of surgery has no statistical difference on the symptom and the QOL status. Conclusion The patients become better one month after surgery, and the improvements on the symptom and the QOL status between the different kinds of surgery are the same, so we suggest to choose the reformed Nasal endoscope surgery.