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糖皮质激素在治疗感染性休克中的应用 被引量:6

The applicatioin of glucosteroid in septic shock
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摘要 感染性休克病死率较高。作为感染性休克的辅助治疗,糖皮质激素在感染性休克患者中广泛使用,但其适用人群、使用时间、剂量、疗程一直存在争议。近年来大规模临床试验推荐在感染性休克中使用小剂量糖皮质激素。本文将对近年来糖皮质激素在感染性休克中应用的研究做一综述。 The mortality of septic shock has been reported high. Glucosteroid is widely used in patients with septic shock as one of the assistant therapies of septic shock. However the applied patients, the using time, the duration and the dose of glucosteroid remain controversial. Recently it is recommended using small dose in septic shock according to results of large scale clinical trials. We will review the studies of glucosteroid in septic shock in recent years here.
作者 陈弘 卢洪洲
出处 《中国实用内科杂志》 CAS CSCD 北大核心 2009年第7期656-658,共3页 Chinese Journal of Practical Internal Medicine
关键词 感染性休克 脓毒症 糖皮质激素治疗 肾上腺功能不全 septic shock sepsis glucosteroid therapy adrenal insufficiency
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  • 1Marik PE, Zaloga GP. Adrenal insufficiency during septic shock [ J ]. Crit Care Med, 2003,31 ( 1 ) : 141 - 145.
  • 2Cooper M, Stewart P. Corticosteroid insufficiency in acutely ill patients [ J ]. N Eng J Med,2003,348 ( 8 ) : 727 - 734.
  • 3Margriet M, de Jong FC, Beishuizen A, et al. Relative adrenal insufficiency as a predictor of disease severity, mortality, and beneficial effects of corticosteroid treatment in septic shock [ J ]. Crit Care Med,2007,35 ( 8 ) : 1896 - 1903.
  • 4Hamrahian A, Oseni T, Arafah B. Measurements of serum free cortisol in critically ill patients[ J ]. N Eng J Med, 2004,350 (16) : 1629 - 1638.
  • 5Ho A,Al-Musalhi H,Chapman M,et al. Septic Shock and Sepsis: A Comparison of Total and Free Plasma Cortisol Levels[ J ]. J Clin Endocrinol Metab ,2006,91 ( 1 ) : 105 - 114.
  • 6Annane D, Bellissant E, Bollaert P, et al. Corticostereids for severe sepsis and septic shock: a systematic review and meta-analysis [J]. BMJ,2004,329(7464) :480.
  • 7Dellinger R, Carlet J, Masur H, et al. Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock [ J ]. Crit Care Med ,2004,32 ( 3 ) :858 - 873.
  • 8Annane D, Sebille V, Charpentier C, et al. Effect of Treatment With Low Doses of Hydrocortisone and Fludrocortisone on Mortality in Patients With Septic Shock [J].JAMA, 2002,288 ( 7 ) : 862 - 871.
  • 9Sprung CL, Annane D, Keh D, et al. Hydrocortisone Therapy for Patients with Septic Shock [ J ]. N Engl J Med, 2008,358 (2) : 111 -124.
  • 10Dellinger RP, Levy MM, Carlet JM, et al. Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock:2008[ J]. Crit Care Med,2007,36( 1 ) :297 - 327.

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