产程中应用度冷丁对胎心率及宫缩的影响

The Effect of Dolantin Used during Labor on the Fetal Heart Rate and Uterine Contraction

目的探讨度冷丁对胎心率及宫缩的影响。方法对潜伏期精神紧张或休息、进食不佳的３０例产妇肌内注射度冷丁１００ｍｇ，用胎儿内监护仪监测胎心率及宫腔压力，观察用药后３０分钟、１小时、２小时的胎心率变化及宫缩情况。结果用药３０分钟后胎心率基线有所下降，１～２小时下降明显但仍在正常范围。用药３０分钟后宫腔静止压力下降。用药１小时后，不协调宫缩得以改善，同时，度冷丁对宫缩频率及强度有加强作用。结论潜伏期使用度冷丁能改善产妇一般情况，虽胎心率有所下降但不造成胎儿窘迫；

Objective To investigate the effect of dolantin on fetus and uterine contraction.Methods Thirty pregnant women under stress, restless or fatigue were given dolantin 100 mg i.m. during the latent phase of labor. Internal fetal heart rate (FHR) monitoring and intrauterine pressure measuring were carried out at 30 minutes, 1 hour and 2 hours after medication.Results The baseline FHR showed a decrease 30 minutes after dolantin, and decreased further at 1 and 2 hours though still within normal range. At the same time, the baseline of intrauterine pressure decreased as well at 30 minutes, so hypertonic uterine contractions were improved. One hour later the incoordinate uterine contraction was relieved and the frequency and strength of uterine contraction were enhanced (P<0.01).Conclusion During labor, especially in latent phase, the use of dolantin may improve the general condition of the women. In spite of the decrease of FHR, no fetal distress occurred. Besides, it may enhance the frequency and strength of uterine contraction and relieve the incoordinate uterine contraction.