不良生活事件和应对方式与肺癌发病关系的研究

Areadverse life events and coping styles the etiological factors o f lung cancer?

目的 研究不良生活事件和应对方式与肺癌发病的关系。方法 对 10 1例肺癌与 10 1例肺部良性病变患者分别用量表调查不良生活事件和应对方式并做统计学处理。结果 (1)肺癌组不良事件总分值和消极应对分值均高于对照组 (P<0 .0 1)。 (2 )不良生活事件高分值组肺癌发生的相对危险性 (OR)为 6 .8;以消极应对方式为主组的 OR为 8.2 ;两者同时存在组的 OR上升为 16 .6。 (3) 4 9项生活事件中 ,与肺癌发生有关的不良生活事件为晋升提薪受挫、配偶死亡、家庭经济困难和就业挫折。 (4 )在有不良生活事件总分值和消极应对分值两个变量存在 L ogistic回归模型中 ,其卡方值分别为 3.8996和 17.82 2 4。结论 不良生活事件和消极应对方式可能与肺癌发生有关 ,两因素联合致肺癌的作用大于单一因素的作用。

ObjectiveTo study the relationship between adverse life events or coping stlyes and occurrence of lung cancer.M ethods 101 cases of lung cancer and 101 cases of benign pulmonary dis orders (thecontrol group) were inquired with questionaires of Life Events Scale and Coping Scale. ResultsTotal scores of adverse life ev ents and negative coping scores were higher in patients with lung cancer thanth ose in the control group (P<0.01). The odds ratio were 6.8 and 8.2 in the group of adveres life eventsand the group of negative coping style, resp ectively. But the odds ration rose to 16.6 in the group both having high scores ofadverse life events and negative coping style.Adverse life events causing lun g cancer among 49 items life events weresetbacks about position or salary, deat h of a spouse, the state of a bad family economic and awaiting a job or jobless.χ 2 were 3.8996 and 17.8224 in multiple Logistic regression equation taking total scores of adverse life events andnegative coping scores as independent va riables. Conclusion It is suggested that occurence of lungca ncer could be related to adverse life events and a negative coping style. The co mbination of adverse life events and anegative coping style can increse risk of lung cancer and the latter's affection is more apparent than the former's.