生长激素缺乏但持续增高：垂体柄中断合并垂体多激素缺乏一例报告及文献复习

Continuous growth with undetectable growth hormone level： one case of invisible pituitary stalk and literature review

报道一例垂体柄中断合并垂体多激素缺乏、包括经低血糖刺激试验发现生长激素缺乏、但表现为持续增高的病例。结合文献复习发现，此种非生长激素依赖的身高生长一般有垂体其他激素尤其是促性腺激素缺乏、骨骺未闭合为基础条件。

Normal function of growth hormone-insulin-like growth factor I axis is essential for linear growth after birth. A case of continuous growth with undetectable growth hormone level even under insulinhypoglycemia stimulation was reported. The growth hormone deficiency was due to pituitary stalk interruption combined with deficiency of multiple pituitary hormones. Taken together with reviewed literature, this so-called nongrowth hormone-dependent linear growth was preconditioned by other hormones,especially gonadotropin deficiency, and the unclosed epiphysis.