自身免疫性甲状腺疾病的遗传学发病机制进展
Advances in the genetic pathogenesis of autoimmune thyroid diseases
摘要
自身免疫疾病是遗传和环境相互影响的结果。免疫调节基因和甲状腺特异基因在自身免疫性甲状腺疾病的发病过程中起重要作用。
Autoimnune disease is the result of interplay between genetic and environmental factors, hnmunoregulatory genes and thyroid specific genes play important roles in the pathogenesis of autoimnune thyroid diseases.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2009年第3期358-360,共3页
Chinese Journal of Endocrinology and Metabolism
参考文献18
-
1Jacobin EM,Tomer Y.The genetic basis of thyroid autoimmunity.Thyroid,2007,17:949-961.
-
2Jacohsen EM,Tomer Y.The CD40,CTI,A-4,thyroghlobulin,TSH receptor,and PTPN22 gene quintet and its eontrihution to thyroid autoimmunity:hack to the future.J Autoimmun,2007,28:85-98.
-
3Schneider H,Downey J,Smith A,et al.Reverseal of the TCR stop signal hy CTLA-4.Science,2006,313:1972-1975.
-
4Schneider H,Smith X,Liu H,et al.CTLA-4 disrupts ZAP70 microcluster formation with reduced T cell/APC dwell times and calcium mohilization.Eur J lmmunol,2008,38:40-47.
-
5Kavvoura FK,Akamizu T,Awata T,et al.CTLA-4 gene polymorphisms and autoimmune thyroid disease:A meta analysis.J Clin Endocrinol Metab,2007,92:3162 -3170.
-
6Wang PW,Chen IY,Liu RT,et al.CTLA-4 gene polymorphism and hyperthyroid Graves's disease relapse after antithyroid drug withdrawal:a follow-up study.J Clin Endocrinol Metab,2007,92:2513-2518.
-
7Zaletel K,Krhin B,Gaberscek S.et al.Thyroid autoantiboby production is influenced hy exon Ⅰ and promoter CTLA-4 polymorphisms in patients with Hashimoto's thyroiditis,Int J Immunogenet,2006,33:87-91.
-
8Chistiakov DA,Savost'anov KV,Turakulov RI,et al.Genetic analysis anti functional evaluation of the C/T (-318) amt A/G (-1661)polymorphisms,of the CTLA-4 gene in patients affected with Graves' disease.Clin lmmuno1,2006,118:233-242.
-
9Hsiao JY,tlsieh MC,Tien KJ,et al.Association between A C/T polymnrphism in exon 33 of the thyroglobulin gene is associated with relapse of Graves' hyperthyroidism after antithyroid withdrawal in Taiwan Residents.J Clin Endoerinol Metab.2007.92:3197-3120.
-
10Hodge SE,Ban Y,Strug I J,et al.Possible interaction hetween HLADRbetal and thyruglobulin variants in Graves'disease.Thyroid,2006,16:351-355.
-
1徐浣白,石建华,项平.自身免疫性甲状腺病的遗传及易感性研究进展[J].国际内科学杂志,2007,34(7):422-426.
-
2彭涛,吕平.1型糖尿病细胞和基因治疗研究进展[J].华中医学杂志,2006,30(3):249-250.
-
3李恒,傅振坤,李殿俊.免疫调节基因多态性与乳腺癌关联的研究进展[J].国际免疫学杂志,2007,30(6):389-393. 被引量：3
-
4李为民,刘巍,傅世英.HLA基因多态性与扩张型心肌病遗传易感性研究进展[J].国外医学（遗传学分册）,2005,28(2):118-120. 被引量：1
-
5李杰,黄赤兵,吴军,张艮甫.共刺激阻断剂CTLA-4Ig在体外培养细胞中的表达[J].中国新医药,2003,2(5):15-16.
-
6产前香烟烟雾暴露影响相关特异基因DNA甲基化[J].中华医学信息导报,2009,24(13):14-14.
-
7郑琪,陶然,尚世强.人巨细胞病毒博弈宿主免疫进展[J].病毒学报,2013,29(1):85-91. 被引量：5
-
8黄吉城,李晖,郑夔,陈秋霞,周惠琼,方苓,鄢心革,万卓越,林锦炎,郑焕英,张欣,刁丽梅,李杰,倪汉忠,黄平,钟豪杰,陈经雕,张万里,谢韶英,颜瑾,何剑锋,梁文佳.广东省各类SARS病例标本实验室检测结果与临床诊断结果比较[J].疾病控制杂志,2003,7(4):273-276. 被引量：3
-
9黄赤兵,吴军,方玉华,易绍萱,罗高兴,贺伟峰,陈希炜.腺病毒介导CTLA4Ig基因在体外培养细胞中的表达[J].重庆医学,2002,31(8):684-685. 被引量：5
-
10叶丽燕,关林波,范平,刘兴会,刘瑞,陈瑾歆,朱月,魏星,刘宇,白怀.重度子痫前期患糊S6基因834＋7G／A和＋1332C／T多态性的研究[J].中华医学遗传学杂志,2017,34(1):45-49. 被引量：7
