摘要
目的探讨原发性肝恶性淋巴瘤(PLL)影响预后因素及治疗方法。方法收治1例PLL治疗情况并复习国内外有关PLL治疗病例38例,合计39例。分析PLL预后因素及治疗结果。结果1.孤立性病灶治疗方式有手术局部切除(10例),放射治疗(2例)和联合化疗(3例)。局部复发2例(手术1例,放射1例,剂量8Gy),死亡3例。多发病灶治疗方式有:联合化疗(17例),放射治疗(3例)和未治疗(4例)。治疗病例中,局部复发7例(化疗6例,放射1例,剂量21Gy。死亡10例。2.有B症状者(12例)死亡9例(75%),无B症状者(27例)死亡(3例)(11.1%)(P<0.01)。结论有B症状者、肝内病灶多发者预后差;孤立性病灶者,无论手术、放射或/和化疗都有较好的局部控制。肝内多发病灶者,单纯全身化疗局部复发率高。
おURPOSE To analyse the prognosis and results of PLL treated by various modalities.METHODS A case of primary lymphoma of the liver (PLL) was reported and 38 cases were reviewed from literatures since 1985RESULTS (1)2 of 15 patients with solitary lesion who had operation (10 patients)、radiotherapy (2 patients)、combination chemotherapy (3 patients) had local relapses.3 patients died.7 of 24 patients with multiple lesions treated with radiotherapy (3 patients) or/and combination chemotherapy (17 patients) had recurrence.10 patients died of disease.(2).9 of 12 patients with B symptoms died (75%) and 3 of 24 patients sithout B symptoms died (111%)P<001.CONCLUSION (1) The prognosis of patients with multiple lesions in liver and B symptoms was poor and (2) :The isolated nodule in the liver had a better local control when treated by operation、radiation or chemotherapy.(3) Chemotherapy had a higher relapse rate,radiotherapy may be beneficial for local control.
出处
《中国癌症杂志》
CAS
CSCD
1998年第2期129-131,共3页
China Oncology