幽门螺杆菌感染与糖尿病伴消化道症状患者基因多态性相关性

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摘要幽门螺杆菌(Helicobacter pylori,Hp)是一种微需氧的革兰阴性杆菌,是慢性活动性胃炎、消化性溃疡、胃癌等疾病的主要致病因素。2型糖尿病伴消化道症状患者Hp感染率明显高于正常人群,本文着重探讨到糖尿病伴消化道症状患者Hp易感性SNP位点。

作者吕淼

机构地区辽宁省抚顺市第三医院检验科

出处《中外医疗》 2009年第18期35-36,共2页 China & Foreign Medical Treatment

关键词 2型糖尿病消化道症状幽门螺杆菌感染细胞因子基因多态性

参考文献6

1Gentile S,Turco S,Oliviero B,et al.The role of autonomic neuropathy as a risk factor of helicohaeter[J].Diabetes Res Clin Pract, 1998,42(1):41 - 48.
2Romeo S,Sentinelli F,Capici F,et al,The G-308A variant of the tumor necrosis factor -α (TNF- α )gene is not associated with obesity,insulin resistance and body fat distribution[J].BMC Medical Genetics,2001,2:10.
3Takagi A, Deguchi R, Kobayashi K, Miwa T. Cytokine expressions and H.pylori-associated gastric mucosal lesion[J]. Keio J Med ,2002,51:51 - 52.
4Garza-Gonzalez E, Bosques-Padilla F J, El-Omar E, et al. Role of polymorphic IL-1B, IL-1RN, and TNF-A genes in distal gastric cancer in Mexico[J]. Int J Cancer, 2005,114:237-241.
5Oldenburg B,Diepersloot RJ,Hoekstra JB.High seroprevalence of helieobacter pylori in diabetes mellitus patients[J].Dig Dis Sci,1996,41(3):458 - 461.
6Kozak R,Juhasz E,Horvat G,et al. Helicobacter pylori infection in diabetic patients[J]. Ovr Hetil,1999,140(18):993-995.

中外医疗

2009年第18期

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