1Freemantle SJ,Dragnev KH,Dmitonsky E.The retinoic acid paradox in cancer chemoprevention.J Natl Cancer Imt,2006,98:426-427.
2Testi AM,Biondi A,Lo Coco F,et al.GIMEMA-AIEOPMDA protocol for the treatment of newly diagnosed acute promyelocytic len-kemia(APL) in children.Blood,2005,106:447-453.
3Chung J,Lin C,Smith DE,et al.Restoration of retinoic acid concentration suppresses ethanol-enhanced c-Jun expression and hepatocyte proliferation in rat liver.Carcinogenesis,2001,22:1213-1219.
5Ohsaki Y,Tanno S,Fujita Y,et al.Epidermal growth factor receptor expression correlates with poor prognosis in non-small cell lung cancer patients with p53 overexpression.Oncol Rep,2000,7:603-607.
6Piyathilake CJ,Frost AR,Manne U,et al.Differential expression of growt h factors in squamons cell carcinoma and precancerous lesions of t he lung.Clin Cancer Res,2002,8:734-744.
7Brabender J,Danenberg KD,Metzger R,et al.Epidermal growth factor receptor and HER2-neu mRNA expression in non-small cell lung cancer is con'elated with sunrival.Clin Cancer Res,2001,7:1850-1855.
1Lim J S, Park S H, Jang K L. All-trans retinoic acid induces cellular senescence by up-regulating levels of p16 and p21 via pro-rooter hypomethylation [ J ]. Biochem Biophys Res Commun, 2011, 412(3) : 500 -5.
2Jemal A, Bray F, Center M M, et al. Global cancer statistics[J]. CA Cancer J Clin, 2011,61(2) : 69 -90.
3Herbst R S, Heymach J V, Lippman S M. Lung Cancer[J]. N Engl J Med, 2008, 359(13) : 1367 -80.
4Siegel R, Ward E, Brawley 0, et al. Cancer statistics : the impact of eliminating socioeconomic and racial disparities on premature cancer deaths, 2011[J]. CA Cancer J Clin, 2011, 61 (4): 212 -36.
5Wagner E F, Nebreda A R. Signal integration by JNK and p38 MAPK pathways in cancer development [ J ]. Nat Rev Cancer, 2009, 9(8) : 537 -49.
6Lauricella M, Emanuele S, D'Anneo A, et al. JNK and AP-1 mediate apoptosis induced by bortezomib in HepG2 cells via FasL/ caspase-8 and mitochondria- dependent pathway [ J ]. Apoptosis, 2006, 11 (4) : 607 - 25.
7Anborgh P H, Mutrie J C, Tuck A B, et al. Pre-and post-translational regulation of osteopontin in cancer[ J ]. J Cell CommunSignal, 2011,5(2) : 111 -22.
8Shevde L A, Das S, Clark D W, et al. Osteopontin : an effector and an effect of tumor metastasis [ J]. Curr Mol Med, 2010, 10 (1):71-81.
9Zhao B, Sun T, Meng F, et al. Osteopontin as a potential biomarker of proliferation and invasiveness for lung cancer[ J]. J Cancer Res Clin Oncol, 2011, 137(7) : 1061 -70.