207例尿道炎患者解脲脲原体药敏分析

Analysis on Antibiotic Resistance of Urerplasma urealyticum in 207 Patients with Urethritis

目的了解岳阳地区解脲脲原体(Uu)的耐药性,更合理选择抗生素。方法采用支原体药敏检测试剂盒和支原体固体培养基进行Uu培养、鉴定和药敏检测。结果Uu阳性率为26.3%,强力霉素、环丙沙星、氧氟沙星、四环素、红霉素、阿奇霉素、克拉霉素、原始霉素、交沙霉素耐药率依次为2.4%、76.3%、30.0%、2.4%、3.4%、11.1%、11.1%、2.4%和13.5%。结论岳阳地区对于Uu引起的非淋菌性尿道炎(NGU),首选药物是以强力霉素、四环素、交沙霉素、原始霉素为主,开展体外药敏试验,根据试验结果为临床合理选择治疗药物提供了依据。

Objective To investigate the profile of the drug resistance of Urerplasma urealyticum （Uu） in Yueyang, and to use antibiotics more rationally. Methods To culture and identify Urerplasma urealyticum and test the susceptibility by use of Mycoplasma Susceptibility Testing Kit and Mycoplasma Agar Media. Results The positive rate of Uu was 26.3%, the drug resistance rates for doxcycline, ciprofloxacin, ofloxacin, tetracycline, erythromycin, azithromycin, clarithromycin, pristinamycin, and josamycin were 2.4%, 76.3%, 30.0%, 2.4%, 3.4%, 11.1%, 11.1%, 2.4%, and 13. 5 %, respectively. Conclusions The first advisable drugs for non - gonorrhea urethritis in Yueyang are doxcycline, tetracycline, josamycin, and pristinamycin. The paper also suggests that in vitro susceptibility test is conducive to more rational choices of therapeutic drugs.