二氢麦角隐亭与阿司匹林对短暂性脑缺血发作的疗效比较

Dihydroergocryptine vs aspirin in treating transient ischemic attacks

目的：比较二氢麦角隐亭与阿司匹林对短暂性脑缺血发作的疗效。方法：短暂性脑缺血发作８８例，随机、单盲分为二氢麦角隐亭治疗组４４例（男性１９例，女性２５例，年龄５１±ｓ１０ａ），予二氢麦角隐亭４ｍｇ，ｐｏ，ｂｉｄ；阿司匹林对照组４４例（男性１８例，女性２６例，年龄５０±１０ａ），予阿司匹林肠溶片７５ｍｇ，ｐｏ，ｑｄ，ｈｓ；２组均１２ｗｋ为一个疗程。结果：总有效率治疗组为８９％，对照组为５２％（Ｐ＜０．０５）。

AIM: To determine the effects of dyhydroergocryptine and aspirin on transient ischemic attacks (TIA). METHODS: Eighty-eight patients with TIA were randomly divided into 2 groups: the dihydroergocryptine group and the aspirin group. The dihydroergocryptine group of 44 patients (M 19, F 25, age 51±s 10 a) received dihydroergocryptine 4 mg, po, bid, and the aspirin group of 44 patients (M 18, F 26, age 50±10 a) received aspirin 75 mg, po, qd, hs, both with a course of 12 wk. RESULTS: The total effective rates were 89% in the dihydroergocryptine group and 52% in the aspirin group, respectively (P<0.05). CONCLUSION : Dihydroergocryptine is superior to aspirin in treating TIA.