胸腔置管引流并给药治疗恶性胸腔积液的临床疗效

Chest tube drainage and administration in the treatment of malignant pleural effusion and its clinical significance in the application

目的探讨恶性胸腔积液置管引流并给药物的临床疗效。方法对60例恶性胸腔积液病人应用中心静脉导管胸腔穿刺置管引流,将顺铂(DDP)稀释后注入胸腔内治疗,每周2次。结果完全缓解(CR)19例,部分缓解(PR)32例,总有效率(CR+PR)85%,不良反应轻,以消化道和一过性发热胸痛为主要反应。结论该方法安全,简便,易行,胸腔内给药不良反应少,能有效控制恶性胸液生长,对缓解病情具有积极的临床意义。

Objective Discussion on malignant pleural effusion drainage and to the clinical efficacy of drugs. Methods 60 cases of malignant pleural effusion in patients with central venous catheter chest drainage, To cisplatin （DDP） into the chest cavity diluted treat- ment, 2 times a week. Results Complete remission （CR） 19 cases, Partial remission （PR） 32 cases. The total effective rate （ CR ＋ PR） was 85%, Light adverse reactions. To the digestive tract and one had chest pain and fever as the main reaction. Conclusion This method is safe, simple, easy, Intrapleural administration of fewer adverse reactions, Can effectively control the growth of malignant pleural effusion, Alleviate the condition of the clinical significance of a positive.