不同时点血糖水平对2型糖尿病合并冠心病患者经皮冠状动脉介入治疗预后的影响

The influence of blood glucose level at different timepoint on PCI in patients with diabetes mellitus complicated with coronary heart disease

目的探讨不同时点血糖水平对糖尿病并冠心病患者经皮冠状动脉介入治疗(PCI)预后的影响。方法对1000例糖尿病并冠心病患者PCI术后血糖控制情况进行监测,定期监测其糖化血红蛋白(HbA1c)、空腹血糖(FBG)、餐后2h血糖(2hPG),比较不同血糖水平的患者术后1年内不良心脏事件发生情况,了解影响该类患者PCI预后的因素。结果2hPG、FBG均控制理想的患者组术后1年心肌梗死、再次血运重建、所有原因死亡、心源性死亡、心衰入院等事件发生率显著低于仅2hPG或FBG控制良好或两者均控制不理想的组别,而仅以HbA1c水平为分组标准的两个对照组的预后无显著差异。结论FBG、2hPG水平均是糖尿病并冠心病患者PCI术后预后的重要影响因素。

Objectives To study the influence of different blood glucose level on PCI in patients with diabetes mellitus complicated with coronary heart disease. Methods One thousand cases of diabetes mellitus with coronary heart disease having percutaneous coronary stent implantation （PCI） were selected and watched at different timepoint for blood glucose level including the HbAlc,FBG and 2 hPG, then the difference in incidence rates of cardiovascular accidents during 1 year after PCI was compared in order to find the key factor for prognosis of these patients. Results The in- cidence rate of cardiovascular accidents is significantly lowered in those patients with well controlled FBG and 2 hPG. Condusion The levels of FBG and 2 hPG are key factors influencing the prognosis of patients with diabetes mellitus complicated with coronary heart disease after PCI.