羟丙基-β-环糊精与三氟氯氰菊酯的包合作用研究

Study on the Inclusion Action of Hydroxypropyl-β-cyclodextrin and Cyhalothrin

[目的]研究羟丙基-β-环糊精与三氟氯氰菊酯的包合作用,进而为更好地利用拟除虫菊酯类农药奠定基础。[方法]用液相法制备羟丙基-β-环糊精.三氟氯氰菊酯包合物,用红外光谱法、显微镜观察法对该包合物进行表征。[结果]三氟氯氰菊酯的红外光谱图显示:苯环C-H的伸缩振动吸收峰在3070.08 cm-1处;酯键C=O和苯环C=C的伸缩振动吸收峰分别在1723.95、1585.80、1585.80、1492.84和1447.38 cm-1处;取代苯的吸收峰在1009.24、960.30、813.56、756.84和697.04 cm-1处。羟丙基-β-环糊精.三氟氯氰菊酯包合物的红外光谱图显示:CD羟基的吸收峰在3 400.06 cm-1处;三氟氯氰菊酯苯环C-H的吸收峰在2930.33 cm-1处;酯键C=O的吸收峰在1724.18 cm-1处。显微镜观察发现:包合物溶液的亚甲蓝玻片背景为蓝色,中间分散的均匀细微的透明圆点为包合物的聚集体。[结论]三氟氯氰菊酯与羟丙基-β-环糊精可形成包合物,其包合物可制成以水为基质的农药剂型。

[ Objective ] The aim was to study the inclusion action of hydroxypropyl-β-cyclodextrin and cyhalothrin so as to lay a foundation for utilizing synthetic pyrethroid insecticides better. [ Method] The inclusion complex of hydroxypropyl-β-cyclodextrin and cyhalothrin was prepared by liquid-phase method and it was characterized by infrared spectrometry and microscopic observation. [ Result ] It was shown on the infrared spectrogram of cyhalothrin that the absorption peak of stretching vibration of C - H bond in benzene ring was at 3 070.08 cm^-1, the absorption peaks of stretching vibration of C = O double-bond in ester bond and C = C double-bond in benzene ring were at 1 723.95, 1 585.80, 1 585, 80, 1 492.84 and 1 447.38 cm^-1 and the absorption peaks of substituted benzene were at 1 009.24,960.30,813.56,756.84 and 697.04 cm^-1. It was shown on the infrared spectrogram of inclusion complex of hydroxypropyl-β-cyclodextrin and cyhalothrin that the absorption peak of CD-hydroxyl was at 3 400.06 cm^-1, the absorption peak of C - H bond in benzene ring of cyhalothrin was at 2 930.33 cm^-1 and the absorption peak of C = O doublebond in ester bond was at 1 724.18 cm^-1. It was found through microscopic observation that the background of methylene blue glass with inclusion complex in solution was blue and the even and remote transparent circular points dispersed in the center were the aggregates of inclusion complexes. [ Conclusion ] The inclusion complex could be made from cyhalothrin and hydroxypropyl-β-cyclodextrin and it could be made into pesticide formulation with water as substrate.